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논문 기본 정보

자료유형
학술저널
저자정보
배지혜 (Department of Obstetrics and Gynecology Seoul National University College of Medicine) 이승미 (서울대학교병원) 정영미 (서울대학교병원) 이지선 (Department of Obstetrics and Gynecology Seoul National University College of Medicine) 김의숙 (Department of Obstetrics and Gynecology Seoul National University College of Medicine) 박찬욱 (서울대학교) 전종관 (Department of Obstetrics and Gynecology Seoul National University Hospital) Joong Shin Park (Department of Obstetrics and Gynecology Seoul National University Hospital)
저널정보
대한주산의학회 Perinatology Perinatology Vol.34 No.1
발행연도
2023.3
수록면
9 - 15 (7page)
DOI
https://doi.org/10.14734/PN.2023.34.1.9

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Objective: Recently, several studies reported that metabolic syndrome (MS) can also cause adverse pregnancy outcomes (APOs). However, the evidence regarding relationship between MS and APO is limited in Asian population, although the outcomes after MS has been reported to have ethnic differences. Therefore, this study aimed to evaluate the relationship between MS and APO (gestational diabetes mellitus [DM], pregnancy associated hypertension [HTN], preterm birth [PTB], small for gestational age, large for gestational age [LGA]) in Korean population. Methods: This study is the secondary analysis of the database from a multicenter prospective cohort. The study population was divided into groups with or without MS, and the relationship between APO at delivery was compared. In addition, the risk of APO according to each diagnostic component of MS was examined. Results: The incidence of APO, especially the risk of gestational DM, PTB, LGA, and cesarean delivery was increased in women with MS. In addition, when examining each MS diagnostic component, all of them were associated to the risk of APO. For specific complications, abdominal obesity increased the risk of gestational DM, pregnancy associated HTN, LGA, and cesarean delivery, high blood pressure increased the risk of gestational DM and pregnancy associated HTN, and hyperglycemia increased the risk of gestational DM and PTB, whereas hypertriglyceridemia, and low low-density lipoprotein cholesterol increased only the risk of gestational DM. Conclusion: Pregnant women with MS in early pregnancy had increased risk of APO. Therefore, patient counseling regarding preventive strategies should be discussed in women with MS.

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