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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 118 - 125 (8page)
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초록· 키워드
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Purpose: The pre-pregnancy body mass index (BMI) is associated with adverse neonatal outcomes. However, studies on very low birth weight (VLBW) infants are rare. This study aimed to investigate the effect of maternal pre-pregnancy BMI on VLBW infants. Methods: This retrospective study evaluated singleton VLBW infants born at the CHA Gangnam Medical Center from 2006 to 2016. The neonates were classified into three groups according to the maternal pre-pregnancy BMI: underweight (<18.5 kg/m2), normal weight (≥18.5 to <23 kg/m2), and overweight or obese (≥23 kg/m2). Clinical characteristics and morbidities of mothers and infants were analyzed. Results: A total of 181 infants belonging to underweight (16.6%), normal weight (58.6%), and overweight or obese (24.8%) groups were enrolled. The pre-pregnancy BMI had a significant negative correlation with gestational age (r=−0.198, P=0.001) and a significant positive correlation with the z-score of the birth weight (r=0.078, P=0.001) and body length (r=0.067, P=0.008). The number of extremely preterm infants was significantly higher in the overweight or obese group. The proportion of risk of small for gestational age infants was higher in the underweight group (adjusted odds ratio [OR], 2.958; 95% confidence interval [CI], 1.113 to 7.864), whereas that of infants with severe retinopathy of prematurity was higher in the overweight or obese group (adjusted OR, 9.546; 95% CI, 1.230 to 74.109). Conclusion: In our population of VLBW infants, the pre-pregnancy BMI was associated with gestational age, intrauterine growth, and adverse neonatal outcomes. Therefore, proper weight control before pregnancy is important.
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참고문헌 (33)
참고문헌 신청
Dzakpasu S / 2015 / Contribution of prepregnancy body mass index and gestational weight gain to adverse neonatal outcomes: population attributable fractions for Canada / BMC Pregnancy Childbirth 15:21
Shin D / 2015 / Prepregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small- and large-for-gestationalage infants / J Matern Fetal Neonatal Med 28:1679~1686
Flenady V / 2011 / Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis / Lancet 377:1331~1340
McDonald SD / 2010 / Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and metaanalyses / BMJ 341:c3428
Han Z / 2011 / Maternal underweight and the risk of preterm birth and low birth weight: a systematic review and metaanalyses / Int J Epidemiol 40:65~101
Shin D / 2015 / Prepregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small- and large-for-gestationalage infants / J Matern Fetal Neonatal Med 28:1679~1686
Flenady V / 2011 / Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis / Lancet 377:1331~1340
McDonald SD / 2010 / Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and metaanalyses / BMJ 341:c3428
Han Z / 2011 / Maternal underweight and the risk of preterm birth and low birth weight: a systematic review and metaanalyses / Int J Epidemiol 40:65~101
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