지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.1
- 수록면
- 21 - 32 (12page)
- DOI
- 10.14348/molcells.2023.2157
이용수
초록· 키워드
오류제보하기
MicroRNAs (miRNAs) play cardinal roles in regulating biological pathways and processes, resulting in significant physiological effects. To understand the complex regulatory network of miRNAs, previous studies have utilized massivescale datasets of miRNA targeting and attempted to computationally predict the functional targets of miRNAs. Many miRNA target prediction tools have been developed and are widely used by scientists from various fields of biology and medicine. Most of these tools consider seed pairing between miRNAs and their mRNA targets and additionally consider other determinants to improve prediction accuracy. However, these tools exhibit limited prediction accuracy and high false positive rates. The utilization of additional determinants, such as RNA modifications and RNA-binding protein binding sites, may further improve miRNA target prediction. In this review, we discuss the determinants of functional miRNA targeting that are currently used in miRNA target prediction and the potentially predictive but unappreciated determinants that may improve prediction accuracy.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Genetic features of Haliotis discus hannai by infection of vibrio and virus
Genes & Genomics
2020 .01
-
MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions
Molecules and Cells
2016 .05
-
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing
Genes & Genomics
2023 .02
-
Genomic identification of microRNA promoters and their cis-acting elements in Populus
Genes & Genomics
2016 .01
-
Deep sequencing reveals microRNA signature is altered in the rat epididymis following bilateral castration
Genes & Genomics
2019 .01
-
Identification and comparative analysis of the pearl oyster Pinctada fucata hemocytes microRNAs in response to Vibrio alginolyticus infection
Genes & Genomics
2017 .01
-
Disease-miRNAdb: a manually-curated database for the investigation of the microRNA-human disease relationship
Genes & Genomics
2017 .01
-
In Silico Study of miRNA Based Gene Regulation, Involved in Solid Cancer, by the Assistance of Argonaute Protein
Genomics & informatics
2016 .01
-
Discovery and profiling of microRNAs and their targets in Paulownia ‘Yuza 1’ plants via high-throughput sequencing and degradome analysis
Genes & Genomics
2016 .01
-
Small RNA Transcriptome of Hibiscus Syriacus Provides Insights into the Potential Influence of microRNAs in Flower Development and Terpene Synthesis
Molecules and Cells
2017 .08
-
MicroRNAs in Autoimmune Sjögren's Syndrome
Genomics & informatics
2018 .01
-
Characterization and differential expression of microRNA in skeletal muscle of Laiwu and Yorkshire pig breeds
Genes & Genomics
2017 .01
-
Effective Fluorescent and colorimetric sensor for miRNA
한국진공학회 학술발표회초록집
2019 .08
-
Identification and differential expression of microRNAs in Madin–Darby canine kidney cells with high and low tumorigenicities
Genes & Genomics
2022 .02
-
Comparative study of predicted miRNA between Indonesia and China (Wuhan) SARS-CoV-2: a bioinformatics analysis
Genes & Genomics
2021 .09
-
A simple colorimetric paper sensor for sensitive sensing of miRNA
한국진공학회 학술발표회초록집
2021 .02
-
Identification of MicroRNAs as potential biomarkers for detecting ischemic stroke
Genes & Genomics
2022 .01
-
Physiological responses and small RNAs changes in maize under nitrogen deficiency and resupply
Genes & Genomics
2019 .01
-
Characterization of the dynamic change of microRNA expression in mice hypothalamus during the time of female puberty
Genes & Genomics
2018 .01
-
Visualization and quantification of miRNA using graphene oxide
한국진공학회 학술발표회초록집
2019 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0