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논문 기본 정보

자료유형
학술저널
저자정보
Xu Hui Liang (Jeju National University) Jung Eun Kim (Jeju National University) Nam Ho Lee (Jeju National University)
저널정보
대한화학회 대한화학회지 대한화학회지 제67권 제2호
발행연도
2023.4
수록면
145 - 149 (5page)

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초록· 키워드

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Talipariti hamabo is a plant growing around salt marshes in the Lava Coast region of Jeju Island, Korea. In this study, the extract of T. hamabo leaves was investigated for the anti-inflammatory, anti-oxidative and anti-bacterial activities and their active constituents were identified. In the anti-inflammatory tests using lipopolysaccharide-stimulated RAW264.7 cells, the ethyl acetate (EtOAc) fraction inhibited the nitric oxide production without causing cell toxicity. Moreover, the EtOAc fraction reduced pro-inflammatory cytokines (tumor necrosis factor-α, interleukin-6) as well as prostaglandin E₂. In the anti-oxidative studies with DPPH and ABTS+ radicals, potent scavenging activities were observed in the EtOAc and n-butanol fractions. Upon the anti-bacterial tests using Staphylococcus epidermidis, EtOAc and n-butanol fractions exhibited good activities. Through the phytochemical studies on EtOAc fraction, three components were isolated by repeated column chromatography; oleic acid (1), p-hydroxyphenethyl-trans-ferulate (2), nicotiflorine (3). Based on these results, the extract of T. hamabo leaves can be developed as natural resources for cosmetic applications.

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ABSTRACT
INTRODUCTION
EXPERIMENTAL
RESULTS AND DISCUSSION
CONCLUSION
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