지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 317 - 323 (7page)
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초록· 키워드
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Background: Multidrug-resistant tuberculosis (MDR-TB) is an important global health problem. Furthermore, the time to identify a positive sputum culture is an important risk factor for the spread of tuberculosis, and several factors can predict a prolonged time to culture conversion. Moreover, the relationship between poor nutritional status and infectious disease is clearly established. Therefore, the present study aimed to investigate the association between body mass index (BMI) and sputum culture conversion within 3 months among patients with MDR-TB.
Materials and Methods: We retrospectively evaluated 218 patients with MDR-TB who were treated at a large tuberculosis referral hospital in South Korea between January 2005 and December 2010. The outcome of interest was defined as sputum culture conversion within 3 months, and we analyzed the association between BMI and this outcome.
Results: Among the 218 patients, 53 patients (24.3%) had a low BMI (<18.5 kg/m2). In the multivariate Cox proportional-hazards regression analysis, failure to achieve sputum culture conversion within 3 months was independently associated with having a low BMI (hazard ratio [HR]: 1.741, 95% confidence interval [CI]: 1.006?3.013; P = 0.047) and a positive sputum smear at the initiation of therapy (HR: 8.440, 95% CI: 1.146?62.138, P = 0.036).
Conclusion: Low BMI (<18.5 kg/m2) was an independent risk factor for failure to achieve sputum culture conversion within 3 months among patients with MDR-TB.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
World Health Organization / Global tuberculosis report 2015
World Health Organization / Global tuberculosis report 2014
Park WS / 2015 / Notified tuberculosis status in Korea, 2015 :342~345
Kwon YS / 2008 / Treatment outcomes for HIV-uninfected patients with multidrug-resistant and extensively drug-resistant tuberculosis / Clin Infect Dis 47:496~502
World Health Organization / Companion hand book to the WHO guidelines for the programmatic management of drug-resistant tuberculosis
World Health Organization / Global tuberculosis report 2014
Park WS / 2015 / Notified tuberculosis status in Korea, 2015 :342~345
Kwon YS / 2008 / Treatment outcomes for HIV-uninfected patients with multidrug-resistant and extensively drug-resistant tuberculosis / Clin Infect Dis 47:496~502
World Health Organization / Companion hand book to the WHO guidelines for the programmatic management of drug-resistant tuberculosis
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