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Comparison of Cognitive Control Deficits in Patients with Schizophrenia and Their Unaffected First-Degree Relatives
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조현병 환자와 발병하지 않은 일차친족에서 인지조절 결함의 비교

논문 기본 정보

Type
Academic journal
Author
윤혜림 (경북대학교 의학전문대학 정신건강의학교실) Seonjin Woo (경북대학교 의학전문대학 정신건강의학교실) Sang-Won Lee (경북대학교 의학전문대학 정신의학교실) Seunghee Won (경북대학교)
Journal
Korean Neuropsychiatric Association 신경정신의학 신경정신의학 제56권 제2호 KCI Accredited Journals
Published
2017.5
Pages
61 - 67 (7page)
DOI
https://doi.org/10.4306/jknpa.2017.56.2.61

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Comparison of Cognitive Control Deficits in Patients with Schizophrenia and Their Unaffected First-Degree Relatives
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Research history (3)

2018

Comparison of Cognitive Controls in Patients with Bipolar I Disorder and Their Unaffected First-Degree Relatives
Yun ,  Hye ,  im and others 10 생물정신의학 2018.01 Academic journal

2017

Comparison of Cognitive Control Deficits in Patients with Schizophrenia and Their Unaffected First-Degree Relatives
Seonjin Woo ,  Sang-Won Lee ,  Seunghee Won and others 0 신경정신의학 2017.05 Academic journal

2016

Comparison of cognitive control deficits in patients with schizophrenia, bipolar I disorder and their unaffected first-degree relatives
윤혜림 의학과 2016.01 Thesis
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Abstract· Keywords

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Objectives This study aimed to identify the differences in the profiles of cognitive control deficits among schizophrenic patients and endophenotypes. Methods The study examined three groups: remitted patients with schizophrenia (n=54), unaffected first-degree relatives of the probands with schizophrenia (n=36), and a healthy control group (n=51), which were all matched for age, sex, and years of education. The AX version of the continuous performance test was used to examine cognitive control. The error rate, correct response times of each subset (AX, BX, AY, BY), and d’ as an indication of the accuracy sensitivity index were calculated. The psychopathology, intelligence, and psychomotor speed were also assessed. Results Patients with schizophrenia showed significantly poorer error rates and d’ in the AX and BX subsets than the others. They showed more delayed correct response times than the healthy control group in all subsets. The first-degree relatives also showed more delayed correct response times in the BX and AY subsets than the healthy control group, but were similar to the patients. Conclusion These findings suggest that cognitive control is impaired in schizophrenia and endophynotypes possibly share this delayed information processing from the higher loading states of cognitive control.
#조현병 #인지조절 #AX-CPT #일차친족 #내적표현형 #Schizophrenia #Cognitive control #AX-CPT #First-degree relatives #Endophenotype

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김도훈 / 2014 / 조현병 환자와 발병하지 않은 일차친족에서 신경인지의 결함 / 생물정신의학 21(2):65~73 dbpia 안용민 / 2005 / 한글판 Montgomery-Åsberg 우울증 평가 척도의 표준화 연구 / 신경정신의학 44(4):466~476 google schola 김도훈 / 2015 / Shared and Distinct Neurocognitive Endophenotypes of Schizophrenia and Psychotic Bipolar Disorder / Clinical Psychopharmacology and Neuroscience 13(1):94~102 google schola

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