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논문 기본 정보

자료유형
학술저널
저자정보
신희현 (중앙보훈병원 정신건강의학과) 최진희 (중앙보훈병원 정신건강의학과) 소형석 (중앙보훈병원 정신건강의학과) 최하연 (중앙보훈병원 정신건강의학과) 박용천 (한양대학교 구리병원 정신건강의학과) Chay Hoon Tan (싱가포르 국립대학교병원 약제부) Shih-ku Lin (타이베이 시립연합병원 정신건강의학센터) Naotaka Shinfuku (세이난 가쿠인대학 인문과학부 사회복지학과) 박선철 (인제대학교) 김기원 (중앙보훈병원 정신건강의학과)
저널정보
대한신경정신의학회 신경정신의학 신경정신의학 제59권 제3호
발행연도
2020.1
수록면
277 - 284 (8page)

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Objectives This study aimed to identify differences between bipolar disorder patients who experienced cognitive side effects and those who did not experience cognitive side effects due to prescription of mood stabilizers. Methods This study analyzed 350 Korean adults who were diagnosed with bipolar disorder and prescribed mood-stabilizing drugs. The patients were divided into two groups?patients who experienced cognitive side effects and those who did not experience cognitive side effects. We also compared the demographic and clinical characteristics between both groups. Results The number of patients with an untreated illness longer than 1 year was higher in the group of patients who experienced cognitive side effects compared to the group of patients who did not experience cognitive side effects. Further, the number of patients with manic symptoms at onset was higher in the group of patients who experienced cognitive side effects compared to the group of patients who did not experience cognitive side effects. In addition, the proportion of patients in remission was higher in the group of patients who experienced cognitive side effects compared to the group of patients who experienced no cognitive side effects. However, there was no significant difference regarding the type of mood stabilizer used between the groups. On the other hand, more people experienced cognitive side effects as the valproic acid dosage increased. Conclusion Our findings suggest that there are clinical and demographic differences between people who experienced cognitive side effects and those who did not experience cognitive side effects due to prescription of mood stabilizers.

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