메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Cosmin Ioan Faur (“Iuliu Hatieganu” University of Medicine and Pharmacy) Horatiu Rotaru (“Iuliu Hatieganu” University of Medicine and Pharmacy) Ciprian Osan (“Iuliu Hatieganu” University of Medicine and Pharmacy) Ancuta Jurj (“Iuliu Hatieganu” University of Medicine and Pharmacy) Rares Calin Roman (“Iuliu Hatieganu” University of Medicine and Pharmacy) Madalina Moldovan (“Iuliu Hatieganu” University of Medicine and Pharmacy) Magdalena Chirila (“Iuliu Hatieganu” University of Medicine and Pharmacy) Mihaela Hedesiu (“Iuliu Hatieganu” University of Medicine and Pharmacy)
저널정보
대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제43권
발행연도
2021.12
수록면
1 - 11 (11page)
DOI
10.1186/s40902-021-00303-9

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: MicroRNAs (miRs) are small, non-coding mRNA molecules which regulate cellular processes in tumorigenesis. miRs were discovered in extracellular environment and biological fluids, carrying marks of head and neck squamous cellcarcinoma (HNSCC). They were also identified in abundance in salivary exosomes, in which they are protected by exosomelipid barrier against enzymatic injuries and therefore, the accuracy of exosomal miR-based cancer detection increase. Thissystematic review aimed to reveal and inventorize the most reliable exosomal miRNAs in saliva samples which can be usedas novel biomarkers for early detection of HNSCC. Materials and methods: A systematic literature search, according to PRISMA guideline, was performed on Pubmed andGoogle Academic libraries, based on specific keywords. Original articles published between 2010 and 2021 were selected. The quality of each paper was assessed using the Quality Evaluation Scoring Tool. Results: At the end of selection process, five studies met the inclusion criteria. These studies analyzed twelve salivaryexosomal miRs, presenting different methods of exosome and miR identification for HNSCC detection. A comprehensiveexplanation of the miR pathways of action was drawn and illustrated in this review. Conclusion: Exosomal miRs are promising biomarkers for oral cavity and oropharyngeal cancer detection. miR-10b-5p, miR486-5p, miR-24-3p and miR-200a stand as the most useful ones in saliva sample examination

목차

등록된 정보가 없습니다.

참고문헌 (0)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0