지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research Allergy, Asthma & Immunology Research Vol.14 No.3
- 발행연도
- 2022.5
- 수록면
- 339 - 343 (5page)
- DOI
- 10.4168/aair.2022.14.3.339
이용수
초록· 키워드
오류제보하기
Phthalates are one of the most commonly used endocrine disruptors and have been considered a risk factor for respiratory disease including asthma. However, it is not yet known how they are related to urticaria. We investigated the association between phthalate exposure and urticaria in 10 healthy controls and 20 adult patients with active urticaria. The urinary levels of mono-n-butyl phthalate (MnBP), mono-2-ethyl-5-carboxypentyl phthalate (MECPP), mono-(2-ethyl-5-oxohexyl) phthalate, and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) were measured by using high performance liquid chromatography tandem mass spectrometry, and mast cell releasability was determined after phthalate treatment. The levels of phthalate metabolites, especially di-ethylhexyl phthalate (DEHP), are significantly increased in the urine of patients with urticaria compared to the healthy controls. The release of β-hexosaminidase in human mast cells is more significantly increased by MnBP, mono-benzyl phthalate, MEHHP, and MECPP compared to the negative controls; interestingly, the highest secretion of β-hexosaminidase is observed after the lowest stimulation of MECPP. Phthalates, including DEHP, may act as aggravating factors for chronic spontaneous urticaria and can be used as potential therapeutic targets in future studies.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Risk assessment of di(2-ethylhexyl)phthalate in the workplace
환경독성보건학회 심포지엄 및 학술대회
2016 .06
-
Effects of maternal exposure to di(2-ethylhexyl) phthalate (DEHP) on susceptibility to juvenile asthma in mouse model
한국실험동물학회 학술발표대회 논문집
2016 .08
-
Distribution of urinary DEHP metabolites in obese children
환경독성보건학회 심포지엄 및 학술대회
2019 .04
-
Effects of Di(2-ethylhexyl)phthalate on Bone Metabolism in Ovariectomized Mice
대한골대사학회지
2019 .01
-
Temporal trends of di(2-ethylhexyl) phthalate exposure and allergic disease in the Korean general population
환경독성보건학회 심포지엄 및 학술대회
2023 .05
-
Risk assessment of di(2-ethylhexyl) phthalate in the workplace
Environmental Analysis Health and Toxicology
2016 .12
-
Association between urinary phthalate metabolites and obesity in adult Korean population: Korean National Environmental Health Survey (KoNEHS), 2012-2014
대한직업환경의학회지
2019 .09
-
Prevalence and Risk Factors of Urticaria With a Focus on Chronic Urticaria in Children
Allergy, Asthma & Immunology Research
2017 .01
-
DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption
Endocrinology and Metabolism
2021 .01
-
한국 소아 청소년에서의 소변 비스페놀 A와 프탈레이트 대사체 농도와 연령에 따른 변화
환경독성보건학회 심포지엄 및 학술대회
2016 .06
-
Associations of Phthalate Metabolites and Bisphenol A Levels with Obesity in Children: The Korean National Environmental Health Survey (KoNEHS) 2015 to 2017
Endocrinology and Metabolism
2022 .04
-
Guideline of Chronic Urticaria Beyond
Allergy, Asthma & Immunology Research
2016 .01
-
Vitamin D as a Marker for Disease Severity in Chronic Urticaria and Its Possible Role in Pathogenesis
Annals of Dermatology
2015 .01
-
두드러기의 분류와 진단
대한내과학회지
2019 .08
-
Screening for Autoimmune Comorbidities in Patients With Chronic Spontaneous Urticaria: Which Tests to Whom
Allergy, Asthma & Immunology Research
2021 .01
-
Impact of Chronic Urticaria on the Self-Assessed Health Status
Allergy, Asthma & Immunology Research
2020 .01
-
고려홍삼의 조사포닌이 Di(2-ethylexyl phthalate에 의해 유발된 호흡기독성에 미치는 영향
동의생리병리학회지
2024 .08
-
Stability study of docetaxel solution (0.9%, saline) using Non-PVC and PVC tubes for intravenous administration
생체재료학회지
2015 .03
-
Can Body Mass Index and/or Waist Circumference Be the Risk Factors of Chronic Spontaneous Urticaria?: A Nationwide Population-Based Study
Annals of Dermatology
2019 .01
-
두드러기 소아 환자에서의 흡입 및 식품항원 감작과비타민 D 관련성
Allergy Asthma & Respiratory Diseases
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0