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자료유형
학술저널
저자정보
Hye Ji Yoon (Semyung University) So Hyeon Park (Semyung University) Hwa Jin Lee (Semyung University)
저널정보
한국생약학회 Natural Product Sciences Natural Product Sciences Vol.25 No.2
발행연도
2019.6
수록면
143 - 149 (7page)

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Eucommiae Cortex (EC), bark of Eucommia ulmoides, has been known as a traditional medicine to regulate hypertension and immune system. Because silk of gum in the EC blocks the release of active ingredients, EC generally has been utilized after processing with carbonization or salt-water to breakdown it. This study aimed to investigate the differences of non-processed EC and processed EC on antioxidant and anticancer properties. Antioxidant capacity was assessed by measuring the content of total polyphenols, reducing power, and ABTS radical scavenging effect. And anticancer effects were examined by evaluating the viability of pancreatic cancer cells and wound healing ability. The results demonstrated that processed EC contained more content of polyphenols and exhibited more potent reducing power and radical scavenging effect than non-processed EC. In addition, processed EC more efficiently inhibited proliferation and migration of pancreatic cancer cells. These results suggest that processing of medicinal plants can improve the biological properties such as antioxidant or anticancer activity, which may lead to the development of herbal medicine treatment technology.

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Abstract
Introduction
Experimental
Result and Discussion
References

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