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논문 기본 정보

자료유형
학술저널
저자정보
Kang Hye Seon (Department of Internal Medicine College of Medicine The Catholic University of Korea Seoul Korea.) Kim Jae Yeol (Department of Internal Medicine College of Medicine Chung-Ang University Seoul Korea.) 박혜정 (연세대학교) Jung Jae-Woo (Department of Internal Medicine College of Medicine Chung-Ang University Seoul Korea.) Choi Hye Sook (Department of Internal Medicine Kyung Hee University Medical Center Seoul Korea.) Park Jong Sook (Department of Internal Medicine College of Medicine Soonchunhyang University Bucheon Korea.) Park Joo Hun (Department of Pulmonary and Critical Care Medicine Ajou University School of Medicine Suwon Korea.) Lee Sang Haak (Department of Internal Medicine Eunpyeong St. Mary's Hospital College of Medicine The Catholic Univ) Chun Eun Mi (Department of Internal Medicine College of Medicine Ewha Womans University Seoul Korea.) Cho Yoojung (Department of Applied Statistics Chung-Ang University Seoul Korea.) Rhee Eunhee (Department of Applied Statistics Chung-Ang University Seoul Korea.) Hwang Beom Seuk (Department of Internal Medicine College of Medicine Ewha Womans University Seoul Korea.) Korean Smoking Cessation Study Group (Korean Smoking Cessation Study Group)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.48
발행연도
2021.12
수록면
1 - 9 (9page)
DOI
10.3346/jkms.2021.36.e331

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Background: This study aimed to investigate the association between e-cigarette (EC) use and development of acute severe pneumonia in the Korean population using a national database. Methods: We conducted a retrospective analysis using linkage of data between the Korean National Health and Nutrition Examination Survey (KNHANES) and the National Health Insurance Service (NHIS) administrative claims database. The primary endpoint of this study was development of severe pneumonia requiring hospital admission according to EC use during the study period. The secondary endpoints were in-hospital mortality, intensive care unit (ICU) admission, ventilator care, and days of hospital stay. Results: The final analysis included 28,950 individuals, of which 578 (2.0%) were EC users. EC users were younger and more often male than non-EC users. The EC users showed higher level of education and household income and had fewer comorbidities. Severe pneumonia was noted in 37 of 28,372 non-EC users (0.13%), but there were no occurrences of severe pneumonia in EC users. The incidence of pneumonia occurrence was not different between the two groups (P = 1.000). Conclusions: Since e-cigarette or vaping use-associated lung injury (EVALI) is most likely included in acute severe pneumonia occurring within 3 months of EC use, it is considered that there might be no EVALI patients in Korea during the investigation period. A large-scale, prospective study is necessary to evaluate the association between EC use and acute lung injury.

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