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논문 기본 정보

자료유형
학술저널
저자정보
Da-Yea Song (Seoul National University College of Medicine) Dabin Kim (Seoul National University Bundang Hospital) Hannah J. Lee (Seoul National University Bundang Hospital) Guiyoung Bong (Seoul National University Bundang Hospital) Jae Hyun Han (Seoul National University Bundang Hospital) Hee Jeong Yoo (Seoul National University College of Medicine)
저널정보
대한소아청소년정신의학회 소아청소년정신의학 소아청소년정신의학 제33권 제2호
발행연도
2022.4
수록면
35 - 40 (6page)

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초록· 키워드

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Objectives: Restricted and repetitive behaviors (RRBs) are a core symptom in the diagnosis of autism spectrum disorder (ASD). The complexity of behavioral patterns has called for the creation of phenotypically homogeneous subgroups among individuals with ASD. The purpose of this study was 1) to investigate the different types of RRBs and 2) to explore whether subgroups created by RRBs would show unique levels of functioning in toddlers and young children with ASD.
Methods: A total of 313 children with ASD, aged 12–42 months were included in the analysis. The Autism Diagnostic Interview-Revised was used to obtain information on the different types of RRBs by grouping 15 items into six categories. The Vineland Adaptive Behaviors Scale, a parent-reported questionnaire, was used to measure adaptive functioning. A portion of the children were analyzed separately for verbal-related RRBs based on their expressive language level. Two-step cluster analysis using RRB groups as features was used to create subgroups. Analysis of covariance while covarying for age and language was performed to explore the clinical characteristics of each cluster group.
Results: Sensory-related RRBs were the most prevalent, followed by circumscribed interests, interest in objects, resistance to change, and repetitive body movements. A subset of the children was analyzed separately to explore verbal-related RRBs. Four cluster groups were created based on reported RRBs, with multiple RRBs demonstrating significant delays in adaptive functioning.
Conclusion: Heterogeneity of RRBs emerges at a young age. The different patterns of RRBs can be used as valuable information to determine developmental trajectories with better implications for treatment approaches.

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INTRODUCTION
METHODS
RESULTS
DISCUSSION
CONCLUSION
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UCI(KEPA) : I410-ECN-0101-2022-516-001354379