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자료유형
학술저널
저자정보
Van-Long Truong (Kyungpook National University) Woo-Sik Jeong (Kyungpook National University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.46 No.2
발행연도
2022.3
수록면
214 - 224 (11page)

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초록· 키워드

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Red ginseng oil (RGO), rather than the conventional aqueous extract of red ginseng, has been receiving much attention due to accumulating evidence of its functional and pharmacological potential. In this review, we describe the key extraction technologies, chemical composition, potential health benefits, and safety of RGO. This review emphasizes the proposed molecular mechanisms by which RGO is involved in various bioactivities. RGO is mainly produced using organic solvents or supercritical fluid extraction, with the choice of method greatly affecting the yield and quality of the end products. RGO contains a high unsaturated fatty acid levels along with considerable amounts of lipophilic components such as phytosterols, tocopherols, and polyacetylenes. The beneficial health properties of RGO include cellular defense, antioxidation, anti-inflammation, anti-apoptosis, chemoprevention, hair growth promotion, and skin health improvement. We propose several molecular mechanisms and signaling pathways that underlie the bioactivity of RGO. In addition, RGO is regarded as safe and nontoxic. Further studies on RGO must focus on a deeper understanding of the underlying molecular mechanisms, composition-functionality relationship, and verification of the bioactivities of RGO in clinical models. This review may provide useful information in the development of RGO-based products in nutraceuticals, functional foods, and functional cosmetics.

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ABSTRACT
1. Introduction
2. Extraction of RGO
3. Chemical composition of RGO
4. Biological activities of RGO and their underlying mechanisms
5. Safety of RGO
6. Conclusions
References

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UCI(KEPA) : I410-ECN-0101-2022-524-001132764