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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 150 - 158 (9page)
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Objectives: Although Campylobacter is the main cause for bacterial acute gastroenteritis (AGE), there has been no notable clinical research into it, especially for Korean children. In this study, we share our experience of clinical, laboratory and image findings with Campylobacter AGE. Methods: Between May 2013 and June 2016, children diagnosed as having Campylobacter AGE were retrospectively enrolled in our study. Campylobacter AGE was considered diagnosed when a patient had symptoms of bacterial AGE and a positive Campylobacter result in stool using multiplex PCR. Results: Among 539 patients with suspected bacterial AGE, 31 (5.8%) patients had a positive result for Campylobacter. The average age of the 31 patients was 10.2 ± 5.0 years with a range between 1.1 and 16.9 years. Eighteen (58%) of the total patients were hospitalized between June and August. Diarrhea (93.5%), abdominal pain (83%) and fever (83%) were common symptoms. For 20 patients (65%), diarrhea lasted for less than three days, and fever lasted for 2.1 days on average. Among the 20 patients subjected to imaging studies, 12 patients (60%) showed bowel wall thickening on the right side of colon. In blood tests of 30 patients, 22 (73%) and 29 (97%) patients exhibited leukocytosis and elevated C-reactive protein, respectively. During treatment for Campylobacter AGE, prediagnostic empirical antibiotics were used for 6 (19%) patients. All patients recovered without complications. Conclusions: Among the children with suspected bacterial AGE, 5.8% had a positive result on Campylobacter in stool using multiplex PCR. Therefore, we observe that Campylobacter AGE should be considered in school-age children who have diarrhea, fever, and abdominal pain.
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참고문헌 (16)
참고문헌 신청
Lee J / 2015 / Detection of Bacterial and Viral Pathogens in Stool Specimens Using Multiplex PCR / J Lab Med Qual Assur 37:141~147
유준환 / 2010 / Epidemiology of Campylobacter jejuni Outbreak in a Middle School in Incheon, Korea / Journal of Korean Medical Science 25(11):1595~1600
이승옥 / 2013 / 다중 중합효소연쇄반응법을 이용한 급성 감염성 설사의 원인세균 13종 및 바이러스 5종 검출 / Annals of Clinical Microbiology 16(1):33~38
나소영 / 2002 / 소아에서 비장티푸스성 살모넬라 위장관염의 임상양상과 항생제 내성률에 대한 연구 / Pediatric Gastroenterology, Hepatology & Nutrition 5(2):150~158
Dey SK / 2012 / Comparison of immunochromatography, PCR and culture methods for the detection of Campylobacter bacteria / J Microbiol Methods 91:566~568
유준환 / 2010 / Epidemiology of Campylobacter jejuni Outbreak in a Middle School in Incheon, Korea / Journal of Korean Medical Science 25(11):1595~1600
이승옥 / 2013 / 다중 중합효소연쇄반응법을 이용한 급성 감염성 설사의 원인세균 13종 및 바이러스 5종 검출 / Annals of Clinical Microbiology 16(1):33~38
나소영 / 2002 / 소아에서 비장티푸스성 살모넬라 위장관염의 임상양상과 항생제 내성률에 대한 연구 / Pediatric Gastroenterology, Hepatology & Nutrition 5(2):150~158
Dey SK / 2012 / Comparison of immunochromatography, PCR and culture methods for the detection of Campylobacter bacteria / J Microbiol Methods 91:566~568
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