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학술저널
저자정보
Amal A. Gharamti (Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon.) Nour Moukalled (Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon.) Taher Ali (Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon.) Kanafani Zeina A. (Department of Internal Medicine American University of Beirut Medical Center Beirut Lebanon.)
저널정보
대한감염학회 Infection and Chemotherapy Infection and Chemotherapy 제52권 제3호
발행연도
2020.1
수록면
415 - 420 (6page)

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A 30-year-old woman with a past medical history of autoimmune hemolytic anemia presented with fever. Blood cultures grew Campylobacter. Her medical history was significant for four prior episodes of Campylobacter gastroenteritis and bacteremia. She received ciprofloxacin for the index presentation, then Meropenem de-escalated to doxycycline 6 months later following recurrence of Campylobacter. This prompted investigation for an immunodeficiency disorder. She was found to have hypogammaglobulinemia. Her Campylobacter infections resolved following the administration of intravenous immunoglobulins every 3 weeks. She did not have recurrence of Campylobacter during 5 years of follow-up. A literature search revealed additional four case reports of six hypogammaglobulinemic adult individuals presenting with recurrent Campylobacter infections. Three patients were already on intravenous immunoglobulin (IVIG) when Campylobacter infection occurred, and two patients achieved clinical cure following therapy with imipenem and IVIG. This case report highlights the importance of suspecting hypogammaglobulinemia in patients with recurrent Campylobacter infections, as this is sometimes the first manifestation of the condition.

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