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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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초록· 키워드
오류제보하기
Recent guidelines for the treatment of thyroid nodules and differentiated thyroid cancer include active surveillance as an alternative option for the treatment of low-risk papillary thyroid microcarcinoma (PTMC). PTMC is defined as having a tumor diameter of ≤1 cm, and low-risk PTMC is defined as PTMC without currently known risk factors (e.g., metastases, local invasion, or cytologic evidence of aggressive disease). Some researchers have suggested that active surveillance can be the first-line treatment of low risk PTMC based on reports showing that the oncological outcomes of active surveillance and immediate surgery were similarly excellent and that immediate surgery can occasionally be accompanied by surgical complications. Nonetheless, many concerns still exist about the full implementation of active surveillance in current clinical practice because the biology of PTMC still has not been fully elucidated and there is little evidence regarding the long-term prognosis of active surveillance. In this review, we discuss the current concept of low-risk PTMC and its treatment modalities, comparing immediate surgery and active surveillance in terms of clinical applications, prognosis, adverse effects, quality of life, and medical costs. This review aims to enable healthcare providers to provide patients with well-balanced information about immediate surgery and active surveillance for the treatment of low-risk PTMC.
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참고문헌 (37)
참고문헌 신청
Haugen BR / 2016 / 2015 American Thyroid Asso-ciation management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer / Thyroid 26:1~133
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19:1167~1214
Ito Y / 2007 / A therapeutic strategy for incidentally detected papillary microcarcinoma of the thyroid / Nat Clin Pract Endocrinol Metab 3:240~248
Harach HR / 1985 / Occult papillary carcinoma of the thyroid: a "normal" finding in Finland: a systematic autopsy study / Cancer 56:531~538
Thorvaldsson SE / 1992 / Latent thyroid carcinoma in Iceland at autopsy / Pathol Res Pract 188:747~750
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules / 2009 / Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer / Thyroid 19:1167~1214
Ito Y / 2007 / A therapeutic strategy for incidentally detected papillary microcarcinoma of the thyroid / Nat Clin Pract Endocrinol Metab 3:240~248
Harach HR / 1985 / Occult papillary carcinoma of the thyroid: a "normal" finding in Finland: a systematic autopsy study / Cancer 56:531~538
Thorvaldsson SE / 1992 / Latent thyroid carcinoma in Iceland at autopsy / Pathol Res Pract 188:747~750
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