지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 195 - 201 (7page)
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초록· 키워드
오류제보하기
Study Design: Experimental study in an animal model. Purpose: This study aims to evaluate the hemostatic properties of four common hemostatic materials including the chitosan clot pad, absorbable gelatin sponge, cellulose membrane, and gauze on peridural bleeding using a rat model. Overview of Literature: Intraoperative bleeding during spinal surgery can lead to morbidities. Hemostatic materials have been developed, but the efficacy of these materials on peridural bleeding remains unclear. Methods: Forty 8-week-old Sprague-Dawley rats were used in this study. Under adequate anesthesia, each rat was posteriorly dissected to their L5 and L6 spinous processes. Bleeding from muscles and soft tissue dissections was stopped before lumbar bone cutting. Immediately after the L5–L6 laminae were cut and removed, the rats were randomly allocated to receive one of the abovementioned hemostatic materials. All hemostatic materials were placed over the raw surface of cut bone and dura and changed every 60 seconds. The procedure was stopped when there was no further bleeding. Time to staunching and amount of bleeding were recorded for statistical analysis. Results: The respective mean±standard deviation hemorrhage volume and time for the cellulose membrane, gelatin sponge, chitosan pad, and gauze were 1.19±0.44, 1.03±0.72, 0.96±0.57, and 1.98±0.62 mL, respectively, and 2.9±0.6, 2.1±0.6, 1.7±0.5, and 2.9±1.0 minutes, respectively. The overall bleeding volumes for the cellulose membrane, gelatin sponge, and chitosan pad were significantly lower than the overall bleeding volume for gauze. Conclusions: Chitosan clot pads, gelatin sponges, and cellulose membranes have better hemostatic properties than gauze. The chitosan pad had the lowest average bleeding volume, followed by gelatin sponge and cellulose membrane.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Sabel M / 2004 / The use of local agents: Surgicel and Surgifoam / Eur Spine J 13(Suppl 1):S97~S101
Gerald AG / 2007 / Update on hemostasis: neurosurgery / Surgery 142(4 Suppl):S55~S60
Faul F / 2007 / G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences / Behav Res Methods 39:175~191
Pierce AM / 1984 / Surgicel: its fate following implantation / J Oral Pathol 13:661~670
Miller JM / 1961 / An investigation of the chemical reactions of oxidized regenerated cellulose / Exp Med Surg 19:196~201
Gerald AG / 2007 / Update on hemostasis: neurosurgery / Surgery 142(4 Suppl):S55~S60
Faul F / 2007 / G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences / Behav Res Methods 39:175~191
Pierce AM / 1984 / Surgicel: its fate following implantation / J Oral Pathol 13:661~670
Miller JM / 1961 / An investigation of the chemical reactions of oxidized regenerated cellulose / Exp Med Surg 19:196~201
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