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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.20 No.2
- 발행연도
- 2016.1
- 수록면
- 102 - 107 (6page)
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초록· 키워드
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Background: Recent studies report that nursing home elderly (NHE) have significantly lower serum levels of 25-hydroxyvitamin D (25-OHD) than community dwelling elderly (CDE); however, in Korea such studies are lacking. We aimed to compare the vitamin D status between NHE and CDE in Korea. Methods: This study included 203 patients over 65 years, admitted to the geriatric department of Seoul Medical Center between 01/2015 and 12/2015. Their medical records were reviewed for demographic data, type of residence, medical and drug history, serum 25-OHD, albumin, creatinine, and calcium levels, and geriatric assessment results. After excluding 36 subjects who had taken vitamin D supplements, anticonvulsants, or steroids, 33 NHE and 134 CDE were included for final analysis. Results: Almost 80% of subjects showed a vitamin D deficiency (25-OHD <20 ng/mL); 54% were severely deficient (25-OHD <10 ng/mL). NHE had a significantly lower serum 25-OHD level than CDE (5.47±2.95 ng/mL vs. 14.72±11.35 ng/mL, p<0.001). Serum 25-OHD level was related to serum albumin level, the Geriatric Depression Scale score, and the Korean version of the Mini Mental State Examination score (p=0.004, p=0.041, p=0.032, respectively). After adjustment for confounding factors using multiple logistic regression analysis, diagnosis of severe vitamin D deficiency was more likely in NHE than CDE (odds ratio, 8.72; 95% confidence interval, 1.53-49.81). Conclusion: This study suggests a high prevalence of vitamin D deficiency in Korean NHE. To prevent falls and osteoporotic fractures in this population, vitamin D supplementation should be considered.
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참고문헌 (23)
참고문헌 신청
Kulie T / 2009 / Vitamin D: an evidence-based review / J Am Board Fam Med 22:698~706
Calton EK / 2015 / The impact of vitamin D levels on inflammatory status: a systematic review of immune cell studies / PLoS One 10:e0141770
Dobnig H / 2008 / Independent association of low serum 25- hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality / Arch Intern Med 168:1340~1349
Garland CF / 2006 / The role of vitamin D in cancer prevention / Am J Public Health 96:252~261
Spedding S / 2014 / Vitamin D and depression: a systematic review and meta-analysis comparing studies with and without biological flaws / Nutrients 6:1501~1518
Calton EK / 2015 / The impact of vitamin D levels on inflammatory status: a systematic review of immune cell studies / PLoS One 10:e0141770
Dobnig H / 2008 / Independent association of low serum 25- hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality / Arch Intern Med 168:1340~1349
Garland CF / 2006 / The role of vitamin D in cancer prevention / Am J Public Health 96:252~261
Spedding S / 2014 / Vitamin D and depression: a systematic review and meta-analysis comparing studies with and without biological flaws / Nutrients 6:1501~1518
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