지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 143 - 150 (8page)
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초록· 키워드
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Purpose: Vitamin D deficiency is still common in pregnant women and infants, especially preterm infants. This study evaluated the prevalence, characteristics, and prenatal and postnatal complications associated with vitamin D deficiency in preterm infants.
Methods: Preterm infants (gestational age of <32 weeks, delivered between January 2014 and December 2014) were divided into two groups according to umbilical cord blood 25-hydroxyvitamin D concentrations (deficiency group, <20 ng/mL; non-deficiency group, ≥20 ng/mL), and associated factors were evaluated.
Results: The mean concentration of 25-hydroxyvitamin D in the preterm infants was 14.3±9.7 ng/mL. 80% (78 out of 98) of subjects had vitamin D deficiency (<20 ng/mL), and 45% (44 out of 98) of preterm infants had a severe vitamin D deficiency (<10 ng/mL). No seasonal variation was observed in 25-hydroxyvitamin D concentration. Mean gestational age and birth weight were lower in the deficiency group. The serum calcium and alkaline phosphatase (ALP) concentrations, which reflect bone metabolism, were significantly different between the two groups, but not the serum phosphorous concentrations. Maternal prenatal complications and infant complications were not significantly different between the two groups.
Conclusion: The prevalence of vitamin D deficiency is high, and it is a persistent problem among Korean mothers and their newborn infants, especially preterm infants. Thus, it is important to prevent vitamin D deficiency by early detection of the deficiency and supplementation of vitamin D.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Kovacs CS / 2008 / Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies / Am J Clin Nutr 88:520S~528S
Tabesh M / 2013 / Maternal vitamin D status and risk of pre-eclampsia: a systematic review and meta-analysis / J Clin Endocrinol Metab 98:3165~3173
Lacroix M / 2014 / Lower vitamin D levels at first trimester are associated with higher risk of developing gestational diabetes mellitus / Acta Diabetol 51:609~616
Burris HH / 2012 / Plasma 25-hydroxyvitamin D during pregnancy and small-for-gestational age in black and white infants / Ann Epidemiol 22:581~586
Bodnar LM / 2010 / Maternal serum 25-hydroxyvitamin D concentrations are associated with small-for-gestational age births in white women / J Nutr 140:999~1006
Tabesh M / 2013 / Maternal vitamin D status and risk of pre-eclampsia: a systematic review and meta-analysis / J Clin Endocrinol Metab 98:3165~3173
Lacroix M / 2014 / Lower vitamin D levels at first trimester are associated with higher risk of developing gestational diabetes mellitus / Acta Diabetol 51:609~616
Burris HH / 2012 / Plasma 25-hydroxyvitamin D during pregnancy and small-for-gestational age in black and white infants / Ann Epidemiol 22:581~586
Bodnar LM / 2010 / Maternal serum 25-hydroxyvitamin D concentrations are associated with small-for-gestational age births in white women / J Nutr 140:999~1006
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