지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 172 - 178 (7page)
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초록· 키워드
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Background: This study was designed to assess serum vitamin D status (25-OHD) in the fibromyalgia (FM) patients and to compare it with a healthy control group. It also aimed to investigate the correlation of serum vitamin D level with FM symptom severity and invalidation experiences. Methods: A total of 74 consecutive patients with FM and 68 healthy control participants were enrolled. The eligible FM patients completed the Illness Invalidation Inventory (3*I), the Revised Fibromyalgia Impact Questionnaire (FIQR) and a short-form health survey (SF-12). Venous blood samples were drawn from all participants to evaluate serum 25-OHD levels. Mann-Whitney tests and multiple logistic regression analyses were performed and Spearman’s correlations were calculated.Results: 88.4% of FM patients had low levels of serum 25-OHD. FM patients had significantly higher level of serum 25-OHD than the control group (17.24 ± 13.50 and 9.91 ± 6.47 respectively, P = 0.0001). There were no significant correlations between serum 25-OHD levels and the clinical measures of disease impact, invalidation dimensions, and health status. Multiple logistic regression analyses revealed that an increased discounting of the disease by the patient’s spouse was associated with a 4-fold increased risk for vitamin D deficiency (OR = 4.36; 95% CI, 0.95−19.87, P = 0.05). Conclusions: This study showed that although high rates of vitamin D insufficiency or deficiency were seen among FM patients and healthy non-FM participants, but it seems there was no intrinsic association between FM and vitamin D deficiency. Addressing of invalidation experience especially by the patient’s spouse is important in management of FM. (Korean J Pain 2016; 29: 172-8)
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Holick MF / 2007 / Vitamin D deficiency / N Engl J Med 357:266~281
de Rezende Pena C / 2010 / Evaluation of 25-hydroxyvitamin D serum levels in patients with fibromyalgia / J Clin Rheumatol 16:365~369
Straube S / 2010 / Vitamin D for the treatment of chronic painful conditions in adults / Cochrane Database Syst Rev :CD007771
Tandeter H / 2009 / Serum 25-OH vitamin D levels in patients with fibromyalgia / Isr Med Assoc J 11:339~342
Warner AE / 2008 / Diffuse musculoskeletal pain is not associated with low vitamin D levels or improved by treatment with vitamin D / J Clin Rheumatol 14:12~16
de Rezende Pena C / 2010 / Evaluation of 25-hydroxyvitamin D serum levels in patients with fibromyalgia / J Clin Rheumatol 16:365~369
Straube S / 2010 / Vitamin D for the treatment of chronic painful conditions in adults / Cochrane Database Syst Rev :CD007771
Tandeter H / 2009 / Serum 25-OH vitamin D levels in patients with fibromyalgia / Isr Med Assoc J 11:339~342
Warner AE / 2008 / Diffuse musculoskeletal pain is not associated with low vitamin D levels or improved by treatment with vitamin D / J Clin Rheumatol 14:12~16
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