개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 349 - 362 (14page)
이용수
초록· 키워드
오류제보하기
A variety of drugs are continuously or intermittently administered to patients during general or regional anesthesia. Pharmacotherapy should also receive priority compared with several treatment modalities including nerve blocks for chronic pain control. Therefore, pharmacology may be fundamental to anesthesia as well as pain medicine. Pharmacokinetic equations quantitatively evaluating drug transfer in the body are essential to understanding pharmacological principles. In mammillary compartmental models, pharmacokinetic equations are easily derived from a few simple principles. The kinetics of drug transfer between compartments is determined initially. Ordinary, linear differential equations are constructed based on the kinetics. The Laplace transforms of these differential equations are used to derive functions for the calculation of drug amounts in the central or effect compartments in the Laplace domain. The inverse Laplace transforms of these functions are used to obtain pharmacokinetic equations in time domain. In this review, a two-compartment mammillary pharmacokinetic model is used to derive pharmacokinetic equations using the aforementioned principles.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pharmacokinetics after Gastrectomy
대한외과학회 학술대회 초록집
2019 .10
-
신생아 약동학과 약물요법
대한소아응급의학회지
2017 .06
-
An experience on the model-based evaluation of pharmacokinetic drug-drug interaction for a long half-life drug
The Korean Journal of Physiology & Pharmacology
2021 .10
-
A mechanism-based understanding of altered drug pharmacokinetics by gut microbiota
Journal of Pharmaceutical Investigation
2023 .01
-
항생제 Fluoroquinolones의 약동학 및 약력학에 관한 최신 정보
Urogenital Tract Infection
2015 .01
-
Analysis and optimization of drug solubility to improve pharmacokinetics
Journal of Pharmaceutical Investigation
2017 .03
-
신생아중환자의 약동학적 다양성에 영향을 미치는 요인
한국임상약학회지
2017 .01
-
Assessment tool based non-invasive molecular imaging for pharmacokinetic evaluation of oligonucleotides
한국실험동물학회 학술발표대회 논문집
2022 .07
-
A semi-compartmental model describing the pharmacokinetic-pharmacodynamic relationship
Anesthesia and Pain Medicine
2020 .01
-
Medicinal plants and phytochemicals for diabetes mellitus: pharmacokinetic characteristics and herb‑drug interactions
Journal of Pharmaceutical Investigation
2019 .01
-
Pharmacokinetics of polynemoraline C in mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Obesity and anesthetic pharmacology: simulation of target-controlled infusion models of propofol and remifentanil
Korean Journal of Anesthesiology
2021 .12
-
Impact of NR1I2, adenosine triphosphateebinding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers
Journal of Ginseng Research
2019 .06
-
Non-clinical pharmacokinetic behavior of ginsenosides
Journal of Ginseng Research
2019 .06
-
Effect of lactic acid bacteria on the pharmacokinetics and metabolism of ginsenosides in mice
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Pharmacokinetics of enrofloxacin HCl-2H₂O (Enro-C) in dogs and pharmacokinetic/pharmacodynamic Monte Carlo simulations against Leptospira spp.
Journal of Veterinary Science
2018 .09
-
External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old
Journal of Korean Medical Science
2020 .01
-
약물계량학을 이용한 초기임상1상 시험 용량 예측 방법에 대한 비교연구
한국임상약학회지
2016 .01
-
Collaborative Pharmacokinetic–Pharmacodynamic Research for Optimization of Antimicrobial Therapy
Infection and Chemotherapy
2016 .01
-
새로운 11β-HSD1 저해제인 KR-67500의 약물동태
약학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0