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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 628 - 635 (8page)
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This study aimed to investigate the effects of vitamin and antioxidant supplements in the prevention of bladder cancer using a meta-analysis of randomized controlled trials (RCTs). Fourteen RCTs were included in the final analysis. In a fixed-effect meta-analysis, vitamin and antioxidant supplements showed no preventive effect for bladder cancer (relative risk [RR] = 1.04; 95% confidence interval [CI] 0.92–1.17; I2 = 39.7%). Also, there was no preventive effect of these supplements in the subgroup meta-analyses by various factors such as type of supplements, type of cancer prevention, methodological quality, providers of supplements, type of control group, and number of participants. Among the subgroup analyses by type of supplements, beta-carotene supplementation alone marginally increased the risk of bladder cancer (RR = 1.44; 95% CI 1.00–2.09; I2 = 0.0%; n = 3). The current meta-analysis found that vitamin and antioxidant supplements have no preventive effect against bladder cancer.
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참고문헌 (40)
참고문헌 신청
Ferlay J / 2015 / Cancer Incidence and Mortality Worldwide: Sources, methods and major patterns in GLOBOCAN 2012 / Int J Cnacer 136:359~386
Torre LA / 2015 / Global cancer statistics, 2012 / CA Cancer J Clin 65:87~108
Letašiová S / 2012 / Bladder cancer, a review of the environmental risk factors / Environ Health 11(Suppl 1):S11
Burger M / 2013 / Epidemiology and risk factors of urothelial bladder cancer / Eur Urol 63:234~241
Park SY / 2013 / Fruit and vegetable intakes are associated with lower risk of bladder cancer among women in the Multiethnic Cohort Study / J Nutr 143:1283~1292
Torre LA / 2015 / Global cancer statistics, 2012 / CA Cancer J Clin 65:87~108
Letašiová S / 2012 / Bladder cancer, a review of the environmental risk factors / Environ Health 11(Suppl 1):S11
Burger M / 2013 / Epidemiology and risk factors of urothelial bladder cancer / Eur Urol 63:234~241
Park SY / 2013 / Fruit and vegetable intakes are associated with lower risk of bladder cancer among women in the Multiethnic Cohort Study / J Nutr 143:1283~1292
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