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논문 기본 정보

자료유형
학술저널
저자정보
Hang An (Osaka University Graduate School of Medicine, Suita, Japan) Keyang Liu (Osaka University Graduate School of Medicine, Suita, Japan) Kokoro Shirai (Osaka University Graduate School of Medicine, Suita, Japan) Ryo Kawasaki (Osaka University Graduate School of Medicine, Suita, Japan) Akiko Tamakoshi (Hokkaido University, Sapporo, Japan) Hiroyasu Iso (National Center for Global Health and Medicine, Tokyo, Japan)
저널정보
대한암학회 Cancer Research and Treatment Cancer Research and Treatment Vol.56 No.2
발행연도
2024.4
수록면
616 - 623 (8page)
DOI
10.4143/crt.2023.962

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Purpose The association of physical activity with the risk of bladder cancer remains inconsistent among Asian populations. We aimed to examine the association in a large Japanese cohort.Materials and Methods In a population-based prospective cohort study, a total of 50,374 Japanese adults aged 40-79 years without a history of cancer or cardiovascular disease who had information on physical activity from self-administrated questionnaires were used for analysis. We performed Cox proportional hazard models to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for incident bladder cancer after adjusting for several potential confounders.Results During the median 17.5 years of follow-up, 153 incident bladder cancers (116 men and 37 women) were identified. After the multivariable adjustment, HRs (95% CI) of bladder cancer concerning those with recreational sports participation of 1-2 hr/wk, 3-4 hr/wk, and 5 hr/wk and more were 0.67 (0.38-1.20), 0.79 (0.36-1.74), and 0.28 (0.09-0.89), respectively (p for trend=0.017). Compared with mostly sitting at the workplace, occupational physical activity of standing and walking were associated with a lower risk of bladder cancer (HR, 0.53 [95% CI, 0.32 to 0.85]). Hours of daily walking were not associated with the risk. The lower risk of bladder cancer was more evident for recreational sports (HR, 0.33 [95% CI, 0.10 to 1.00]), and for occupational standing and walking activity at work (HR, 0.57 [95% CI, 0.33 to 0.98]) among men.Conclusion Recreational sports participation and occupational physical activity were inversely associated with the risk of bladder cancer among Japanese, especially in men.

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