지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 275 - 284 (10page)
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초록· 키워드
오류제보하기
Purpose: To investigate the efficacy and safety of KBMSI-2, an herbal formula consisting of Ginseng Radix Rubra, Dioscorea tenuipes, Cornus officinalis Sieb. et Zucc., Lycium chinense Mill, and Curcuma longa Linn, for the treatment of erectile dysfunction (ED). Materials and Methods: Patients were instructed to take placebo or 6 g of KBMSI-2 twice per day for 8 weeks, at least 1 hour after food intake. The primary outcome was a change from baseline in erectile function (EF) domain scores of the International Index of Erectile Function (IIEF) questionnaire. Secondary outcome included changes from baseline in all domain scores of the IIEF, scores on the Aging Males' Symptoms scale, and serum total testosterone levels, as well as changes in questions 2 and 3 of the Sexual Encounter Profile, responses to the Global Assessment Question, and changes in the number of ‘yes’ responses on the Androgen Deficiency in Aging Males questionnaire. Results: Patients receiving KBMSI-2 had a statistically significant improvement in baseline IIEF-EF domain scores at 8 weeks compared to the placebo group. Intercourse satisfaction domain and the total IIEF scores also increased in the KBMSI-2 group. However, we could not find any significant differences in other efficacy variables between the groups. Only one patient had an adverse event, which was mild in severity. Conclusions: This preliminary clinical study of KBMSI-2 shows significant improvements in EF and intercourse satisfaction, as measured by the IIEF in patients with ED. Further studies using a larger number of patients in the long term should follow.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Lue TF / 2000 / Erectile dysfunction / N Engl J Med 342:1802~1813
Carvalheira AA / 2012 / Dropout in the treatment of erectile dysfunction with PDE5 : a study on predictors and a qualitative analysis of reasons for discontinuation / J Sex Med 9:2361~2369
Salonia A / 2008 / Acceptance of and discontinuation rate from erectile dysfunction oral treatment in patients following bilateral nervesparing radical prostatectomy / Eur Urol 53:564~570
Ljunggren C / 2008 / Giving patients with erectile dysfunction the opportunity to try all three available phosphodiesterase type 5 inhibitors contributes to better long-term treatment compliance / J Sex Med 5:469~475
Raina R / 2003 / Long-term effect of sildenafil citrate on erectile dysfunction after radical prostatectomy : 3-year follow-up / Urology 62:110~115
Carvalheira AA / 2012 / Dropout in the treatment of erectile dysfunction with PDE5 : a study on predictors and a qualitative analysis of reasons for discontinuation / J Sex Med 9:2361~2369
Salonia A / 2008 / Acceptance of and discontinuation rate from erectile dysfunction oral treatment in patients following bilateral nervesparing radical prostatectomy / Eur Urol 53:564~570
Ljunggren C / 2008 / Giving patients with erectile dysfunction the opportunity to try all three available phosphodiesterase type 5 inhibitors contributes to better long-term treatment compliance / J Sex Med 5:469~475
Raina R / 2003 / Long-term effect of sildenafil citrate on erectile dysfunction after radical prostatectomy : 3-year follow-up / Urology 62:110~115
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