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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 61 - 65 (5page)
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Purpose: Autologous platelet rich plasma (PRP) is used increasingly in a variety of settings. PRP injections have been used for decades to improve angiogenesis and wound healing. They have also been offered commercially in urology with little to no data on safety or efficacy. PRP could theoretically improve multiple urologic conditions, such as erectile dysfunction (ED), Peyronie's disease (PD), and stress urinary incontinence (SUI). A concern with PRP, however, is early washout, a situation potentially avoided by conversion to platelet rich fibrin matrix (PRFM). Before clinical trials can be performed, safety analysis is desirable. We reviewed an initial series of patients receiving PRFM for urologic pathology to assess safety and feasibility. Materials and Methods: Data were reviewed for patients treated with PRFM at our center from November 2012 to July 2017. Patients were observed immediately post-injection and at follow-up for complications and tolerability. Where applicable, International Index of Erectile Function (IIEF-5) scores were reviewed before and after injections for ED and/or PD. Pad use data was collected pre/post injection for SUI. Results: Seventeen patients were identified, with a mean receipt of 2.1 injections per patient. Post-procedural minor adverse events were seen in 3 men, consisting of mild pain at injection site and mild penile bruising. No patients experienced complications at follow-up. No decline was observed in men completing pre/post IIEF-5 evaluations. Conclusions: PRFM appears to be a safe and feasible treatment modality in patients with urologic disease. Further placebo-controlled trials are warranted.
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등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Andia I / 2013 / Platelet-rich plasma for managing pain and inflammation in osteoarthritis / Nat Rev Rheumatol 9:721~730
Jiritano F / 2013 / Ventricular assist device driveline infection: treatment with platelet-rich plasma / Ann Thorac Surg 96:e37~e38
Marck RE / 2014 / Considerations on the use of platelet-rich plasma, specifically for burn treatment / J Burn Care Res 35:219~227
Schiavone G / 2014 / Platelet-rich plasma for androgenetic alopecia: a pilot study / Dermatol Surg 40:1010~1019
Zhou B / 2014 / Protection of colonic anastomosis with platelet-rich plasma gel in the open abdomen / Injury 45:864~868
Jiritano F / 2013 / Ventricular assist device driveline infection: treatment with platelet-rich plasma / Ann Thorac Surg 96:e37~e38
Marck RE / 2014 / Considerations on the use of platelet-rich plasma, specifically for burn treatment / J Burn Care Res 35:219~227
Schiavone G / 2014 / Platelet-rich plasma for androgenetic alopecia: a pilot study / Dermatol Surg 40:1010~1019
Zhou B / 2014 / Protection of colonic anastomosis with platelet-rich plasma gel in the open abdomen / Injury 45:864~868
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The authors reply: Safety and feasibility of platelet rich fibrin matrix injections for treatment of common urologic conditions
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Letter to the editor: Safety and feasibility of platelet rich fibrin matrix injections for treatment of common urologic conditions
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Allogeneic Platelet-Rich Plasma Versus Corticosteroid Injection for the Treatment of Rotator Cuff Disease: A Randomized Controlled Trial
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The use of platelet-rich plasma in management of musculoskeletal pain: a narrative review
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Therapeutic Efficacy of Urethral Sphincter Injections of Platelet- Rich Plasma for the Treatment of Stress Urinary Incontinence due to Intrinsic Sphincter Deficiency: A Proof-of-Concept Clinical Trial
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Platelet-Rich Plasma Injections as a Treatment for Refractory Patellar Tendinosis: A MetaAnalysis of Randomised Trials
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Efficacy and Safety of Vocal Cord Platelet-rich Plasma (PRP) Injection in Patient with Intractable Vocal Cord Disease
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Effectiveness of Autologous Platelet-Rich Plasma for the Healing of Ulcers after Endoscopic Submucosal Dissection
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Does Platelet-rich Plasma Augmentation Following Hip Arthroscopy Improve Outcomes: A Systematic Review
Hip and Pelvis
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Freeze-Dried Platelet-Rich Plasma Induces Osteoblast Proliferation via Platelet-Derived Growth Factor Receptor-Mediated Signal Transduction
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Platelet rich plasma versus corticosteroids for lateral epicondylitis: a meta-analysis of randomized clinical trials
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Intradiscal Injection of Autologous Platelet-Rich Plasma Releasate to Treat Discogenic Low Back Pain: A Preliminary Clinical Trial
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Current clinical applications of platelet-rich plasma in various gynecological disorders: An appraisal of theory and practice
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