지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 14 - 20 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: To evaluate the significance of preoperative and follow-up neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors for recurrence in patients with non-metastatic clear cell renal cell carcinoma (NMCCRCC). Materials and Methods: We retrospectively reviewed the medical records of 309 patients with NMCCRCC who underwent radical or partial nephrectomy. The prognostic significance of various clinicopathological variables, preoperative NLR (pNLR) and PLR (pPLR), and NLR and PLR at recurrence or quasi-recurrence (rNLR and rPLR) for recurrence-free survival (RFS) was analyzed. Results: At mean follow-up of 93 months, 44 patients (14.2%) developed recurrence. In the univariate analysis, clinical presentation, tumor size, pathologic tumor stage, Fuhrman grade, pNLR, pPLR and rNLR were significant prognostic factors for RFS. In the multivariate analysis using pNLR and pPLR as continuous variables, tumor size, pathologic tumor stage and pPLR were independent prognostic factors for RFS. In the multivariate analysis using pNLR and pPLR as dichotomous variables, tumor size, pathologic tumor stage, Fuhrman grade and pNLR ≥1.7 were independent prognostic factors for RFS. In multivariate analyses using rNLR and rPLR, only tumor size and pathologic tumor stage were independent prognostic factors for RFS. In a subset of patients with recurrence or at least 42 months follow-up without recurrence, rNLR ≥1.9 was significantly associated with worse RFS, albeit without independent significance. Conclusions: pNLR and pPLR are independent prognostic factors for RFS in patients with NMCCRCC. We propose that postoperative follow-up NLR of 1.9 and higher with one or more adverse clinicopathological factors should prompt radiologic evaluation for possible metastasis.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Prognostic value of preoperative neutrophil-to-lymphocyte ratio in histological variants of non-muscle-invasive bladder cancer
Investigative and Clinical Urology
2021 .11
-
Prognostic factors in neuroendocrine cervical carcinoma
Obstetrics & Gynecology Science
2016 .01
-
Prognosis of Hepatocellular Carcinoma after Liver Transplantation: Comparative Analysis with Partial Hepatectomy
Journal of Pathology and Translational Medicine
2017 .01
-
Comparison of the Prognostic Factors according to Tumor Size in Small Breast Cancer
대한외과학회 학술대회 초록집
2022 .05
-
The Prognostic Values of Preoperative Tumor Volume and Tumor Diameter in T1N0 Papillary Thyroid Cancer
Cancer Research and Treatment
2017 .01
-
Postresection prognosis of combined hepatocellular carcinoma-cholangiocarcinoma according to the 2010 World Health Organization classification: single-center experience of 168 patients
Annals of Surgical Treatment and Research
2021 .05
-
Is high grade tumor budding an independent prognostic factor in stage II colon cancer?
대한임상종양학회 학술대회지
2022 .02
-
Prognostic factors for recurrence and survival in uterine leiomyosarcoma: Korean single center experience with 50 cases
Obstetrics & Gynecology Science
2019 .01
-
Letter to the editor: Prognostic significance of preoperative and follow-up neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with non-metastatic clear cell renal cell carcinoma
Investigative and Clinical Urology
2019 .01
-
Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix
Journal of Gynecologic Oncology
2018 .01
-
Preoperative neutrophil-to-lymphocyte ratio is a prognostic factor for overall survival in patients with gastric cancer
Annals of Surgical Treatment and Research
2015 .07
-
Neutrophil to Lymphocyte Ratio: A Predictive Marker for Treatment Outcomes in Patients With Rectal Cancer Who Underwent Neoadjuvant Chemoradiation Followed by Surgery
Annals of Coloproctology
2019 .01
-
조기 유방암에서 수술 전 유방초음파 및 유방 자기공명영상검사와 수술 후 병리학적 종양 크기에 대한 비교 연구
Journal of Breast Disease
2020 .01
-
Preoperative Neutrophil to Lymphocyte Ratio as a Prognostic Factor in Patients with Non-metastatic Renal Cell Carcinoma
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Prognostic factors after curative resection hepatocellular carcinoma and the surgeon’s role
Annals of Surgical Treatment and Research
2017 .11
-
Prognostic Factor Analysis of Overall Survival in Gastric Cancer from Two Phase III Studies of Second-line Ramucirumab (REGARD and RAINBOW) Using Pooled Patient Data
Journal of Gastric Cancer
2017 .06
-
Tumor Deposit Should be Considered Significantly as Poor Prognostic Factor in Non-Metastatic Colon Cancer
대한외과학회 학술대회 초록집
2023 .05
-
Gastroenteropancreatic Neuroendocrine Tumors with Liver Metastases in Korea: A Clinicopathological Analysis of 72 Cases in a Single Institute
Cancer Research and Treatment
2015 .01
-
Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients
Journal of Breast Cancer
2020 .01
-
Prognostic Factors for Recurrence and Progression in Korean Non-Muscle-Invasive Bladder Cancer Patients: A Retrospective, Multi-Institutional Study
Yonsei Medical Journal
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0