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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 495 - 495 (1page)
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Rag GTPase, an important regulator of mTORC1 activity, plays an important role in insulin resistance and gluconeogenesis. We investigated the effect of Rag GTPase on hepatic glycogen metabolism using RagA/B liver conditional knockout (LKO) mouse and its regulatory mechanism. Wild-type (WT) and RagA/B LKO mouse were analyzed for hepatic glycogen accumulation and blood glucose levels under fasting/refeeding conditions or streptozotocin (STZ)-induced diabetic conditions. After 10 h fasting, 2 h refeeding RagA/B LKO mouse showed significantly lower blood glucose and liver glycogen contents tha ... 전체 초록 보기
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