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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 361 - 361 (1page)
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Cases of IBD are continuously increasing globally. IBD is directly caused by intestinal barrier dysfunction. Although protocatechuic acid (PCA) has a protective effect on colitis, the molecular mechanisms underlying its contribution to intestinal barrier function remain unknown. TEER and FITC-dextran permeability measurements reveled that PCA suppresses LPS and TNF-α-induced increase in intestinal permeability; ZO-1 and claudin-2 redistribution was also suppressed in the epithelial cell membranes of Caco-2 cells. PCA was found to directly bind ROCK, subsequently ... 전체 초록 보기
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