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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 295 - 295 (1page)
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Chungkookajng fermented with different Bacillus spp. has different efficacies for metabolic functions. It has been reported to have anti-oxidant and anti-inflammatory activities and improves glucose metabolism by potentiating insulin sensitivity and improving β-cell function and mass. Furthermore, amyloid-beta (Aβ) accumulation is increased by brain insulin resistance. The impairment of insulin/IGF-1 signaling mainly in the hippocampus and brain insulin resistance is connected to signals originating in the liver and gut microbiota, known as the gut microbiota-liver-brain axis. It indicates that the changes in the production of short-chain fatty acids by the gut microbiota and proinflammatory cytokines can alter insulin resistance in the liver and brain. Isoflavonoids such as genistein and daidzein are detected in the brain tissues after passing through the blood-brain barrier, where i ... 전체 초록 보기
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