지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 310 - 316 (7page)
이용수
초록· 키워드
오류제보하기
Microarray technology represents a critical new advance in molecular cytogenetics. The development of this approach has provided fundamental insights into the molecular pathogenesis in clinical cytogenetics and has provided a clue to many unidentified or unexplained diseases. The approach allows a comprehensive investigation of thousands and millions of genomic loci simultaneously and enables the efficient detection of copy number alterations. The application of this technology has shown tremendous fluidity and complexity of the human genome, and has provided accurate diagnosis and appropriate clinical management in a timely and efficient manner for identifying genomic alterations. The clinical impact of the genomic alterations identified by microarrays is evolving into a diagnostic tool to identify high-risk patients better and predict patient outcomes from their genomic profiles. The transformation of conventional cytogenetics into an automated discipline will improve diagnostic yield significantly, leading to accurate diagnosis and genetic counseling. This article reviews cytogenetic technologies used to identify human chromosome alterations and highlights the potential utility of present and future genome microarray technology in the diagnosis.
목차
등록된 정보가 없습니다.
참고문헌 (39)
참고문헌 신청
Leonor Arenillas / 2013 / Single nucleotide polymorphism array karyotyping: A diagnostic and prognostic tool in myelodysplastic syndromes with unsuccessful conventional cytogenetic testing / Genes, Chromosomes and Cancer 52(12):1167~1177
Michael R. Speicher / 2005 / The new cytogenetics: blurring the boundaries with molecular biology / Nature Reviews Genetics 6(10):782~792
Sandra Darilek / 2008 / Pre- and postnatal genetic testing by array-comparative genomic hybridization: genetic counseling perspectives / Genetics in Medicine 10(1):13~18
Marilyn M. Li / 2009 / Clinical Application of Microarray-Based Molecular Cytogenetics: An Emerging New Era of Genomic Medicine / The Journal of Pediatrics 155(3):311~317
JI UN KANG / 2012 / Evolving applications of microarray technology in postnatal diagnosis / International Journal of Molecular Medicine 30(2):223~228
Michael R. Speicher / 2005 / The new cytogenetics: blurring the boundaries with molecular biology / Nature Reviews Genetics 6(10):782~792
Sandra Darilek / 2008 / Pre- and postnatal genetic testing by array-comparative genomic hybridization: genetic counseling perspectives / Genetics in Medicine 10(1):13~18
Marilyn M. Li / 2009 / Clinical Application of Microarray-Based Molecular Cytogenetics: An Emerging New Era of Genomic Medicine / The Journal of Pediatrics 155(3):311~317
JI UN KANG / 2012 / Evolving applications of microarray technology in postnatal diagnosis / International Journal of Molecular Medicine 30(2):223~228
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Overview of Cytogenetic Technologies
대한임상검사과학회지
2018 .01
-
Specific bacteriophage of Bordetella bronchiseptica regulates B. bronchiseptica-induced microRNA expression profiles to decrease inflammation in swine nasal turbinate cells
Genes & Genomics
2020 .01
-
Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer
Genes & Genomics
2020 .01
-
Relationship between spatial organization and biological function, analyzed using gene ontology and chromosome conformation capture of human and fission yeast genomes
Genes & Genomics
2016 .01
-
Integrated Genomics and Phenotype Microarray Analysis of Saccharomyces cerevisiae Industrial Strains for Rice Wine Fermentation and Recombinant Protein Production
한국미생물학회 학술대회논문집
2022 .10
-
Attenuation of Postischemic Genomic Alteration by Mesenchymal Stem Cells: a Microarray Study
Molecules and Cells
2016 .04
-
Microarray 분석을 이용한 대하 (Fenneropenaeus chinensis) 유생의 카드뮴 단기 노출에 따른 유전자변화
한국환경과학회지
2015 .05
-
Unlocking biological mechanisms with integrative functional genomics approaches
Molecules and Cells
2024 .01
-
Editorial : In this issue, there are 10 articles: two review articles, six original articles, one clinical genomics, and one application note
Genomics & informatics
2019 .01
-
Genomic and Metabolic Features of Enterococcus faecium Revealed by Pan-genomic and Metatranscriptomic Analysis
한국미생물학회 학술대회논문집
2020 .10
-
Comparison of methods for the proportion of true null hypotheses in microarray studies
CSAM(Communications for Statistical Applications and Methods)
2020 .01
-
Comparison of false discovery rate procedures in microarray studies
한국데이터정보과학회지
2019 .03
-
Genomic Analysis of Microorganisms Isolated from Kimchi and Human
한국미생물학회 학술대회논문집
2019 .04
-
Fungal Genomics in Dermatology
대한의진균학회지
2019 .01
-
Research on the Genomic Functionality Using Industrial Animal-derived Microbial Genome Analysis and Bioinformatics
한국미생물학회 학술대회논문집
2022 .10
-
Identifying Vulnerabilities in Fungal Pathogens through Functional and Chemical Genomic Analyses
한국미생물학회 학술대회논문집
2021 .08
-
An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts
Molecules and Cells
2016 .02
-
Emerging role for R-loop formation in hepatocellular carcinoma
Genes & Genomics
2023 .05
-
Pasteurella multocida specific bacteriophage suppresses P. multocida‑induced inflammation: identification of genes related to bacteriophage signaling by Pasteurella multocida‑infected swine nasal turbinate cells
Genes & Genomics
2020 .01
-
Metastasis associated genomic aberrations in stage II rectal cancer
Genes & Genomics
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0