지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 155 - 160 (6page)
이용수
초록· 키워드
오류제보하기
Torsades de pointes refers to polymorphic ventricular tachycardia (PMVT), which is caused by the suppression of potassium channels owing to genetic and electrolytic abnormalities, resulting in the extension of the QT interval. Symptoms range from spontaneous circulation recovery to fainting and sudden death. Defibrillation, magnesium correction, and the use of lidocaine as an antiarrhythmic agent are recommended as treatments for persistent torsades de pointes. Currently, only amiodarone is available in the ambulance; however, torsades de pointes does not respond efficiently to amiodarone because it suppresses potassium channels and increases the refractory period of the myocardium. Lidocaine, in contrast, reduces the relative refractory period of the myocardium caused by suppressing sodium channels; thus, it inhibits the occurrence of and treats arrhythmia. In cases where PMVT did not respond to defibrillation, the administration of lidocaine showed no difference in survival and discharge rates compared to amiodarone. Thus, ambulances must be equipped with provisions to administer lidocaine.
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Israel CW / 2014 / Mechanisms of sudden cardiac death / Indian Heart J 66(Suppl 1):S10~S17
Passman R / 2001 / Polymorphic ventricular tachycardia, long QT syndrome, and torsades de pointes / Med Clin North Am 85(2):321~341
Sorajja D / 2015 / Optimal antiarrhythmic drug therapy for electrical storm / J Biomed Res 29(1):20~34
Kallergis EM / 2012 / Mechanisms, risk factors, and management of acquired long QT syndrome: a comprehensive review / Scientific World J :212178
Dolenska S / 2009 / Intraoperative cardiac arrest in acquired long QT syndrome / Br J Anaesth 102(4):503~505
Passman R / 2001 / Polymorphic ventricular tachycardia, long QT syndrome, and torsades de pointes / Med Clin North Am 85(2):321~341
Sorajja D / 2015 / Optimal antiarrhythmic drug therapy for electrical storm / J Biomed Res 29(1):20~34
Kallergis EM / 2012 / Mechanisms, risk factors, and management of acquired long QT syndrome: a comprehensive review / Scientific World J :212178
Dolenska S / 2009 / Intraoperative cardiac arrest in acquired long QT syndrome / Br J Anaesth 102(4):503~505
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