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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제59권 제4호
- 발행연도
- 2016.1
- 수록면
- 317 - 322 (6page)
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초록· 키워드
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UV exposure induces matrix metalloproteinases (MMPs) and extracellular matrix-degrading enzymes expression. We studied the protective effect of Rubus occidentalis seed against UVB-generated skin photoaging using human fibroblast cells (CCD-986sk). We used an ELISA kit to measure the supernatents of procollagen type I and MMP-1 in CCD-986sk cells after they were exposed to UVB irradiation. The CCD-986sk cells that were used with RC-E/E after the UVB irradiation caused higher levels of type I procollagen and lesser levels of MMP-1 compared with the control group. Furthermore, the RC-E/E treated group showed lesser MMP-1 levels and higher procollagen type I levels than the untreated counterpart. Therefore, it can be concluded that Rubus occidentalis seed can prevent from skin photoaging.
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참고문헌 (17)
참고문헌 신청
Ahn BN / 2013 / Photo protective effect of libanoridin isolated from Corydalis heterocarpa on UVB stressed human keratinocyte cells / Exp Dermatol 22:155~157
Bae JY / 2008 / Epigallocatechin gallate hampers collagen destruction and collagenase activation in ultraviolet-B-irradiated human dermal fibroblasts : involvement of mitogen-activated protein kinase / Food Chem Toxicol 46:1298~1307
Bennett DC / 2008 / Ultraviolet wavebands and melanoma initiation / Pigm Cell Melanoma Res 21:520~524
Brennan M / 2003 / Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin / Photochem Photobiol 78:43~48
Chen CL / 2011 / Protective effects of Chlorelladerived peptide on UVB-induced production of MMP-1 and degradation of procollagen genes in human skin fibroblasts / Regul Toxicol Pharmacol 60:112~119
Bae JY / 2008 / Epigallocatechin gallate hampers collagen destruction and collagenase activation in ultraviolet-B-irradiated human dermal fibroblasts : involvement of mitogen-activated protein kinase / Food Chem Toxicol 46:1298~1307
Bennett DC / 2008 / Ultraviolet wavebands and melanoma initiation / Pigm Cell Melanoma Res 21:520~524
Brennan M / 2003 / Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin / Photochem Photobiol 78:43~48
Chen CL / 2011 / Protective effects of Chlorelladerived peptide on UVB-induced production of MMP-1 and degradation of procollagen genes in human skin fibroblasts / Regul Toxicol Pharmacol 60:112~119
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