지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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A series of N-substitutedaryl-3-phenylpropanamide derivatives were synthesized and their inhibitory activities on LPS-induced NF-$1{\kappa}B$ transcriptional activity on RAW 264.7 cells were evaluated. Cl substituted derivatives (1e, 1f) have shown more potent activities than parent hit compound KL-1156.
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참고문헌 (14)
참고문헌 신청
Mohammad, Y / 2014 / Plant derived polyphenols, other drugs targeting NF-κB and its therapeutic implications / British Biomedical Bulletin 2:422
Beg, A. A. / 1996 / An essential role for NF-κB in preventing TNF-alpha-induced cell death / Science 274:782
Wu, M. / 1996 / Inhibition of NF-kappaB/ReI induces apoptosis of murine B cells / EMBO J 15:4682
Wang, C. Y / 1996 / TNF and cancer therapy-induced apoptosis / Science 274:784
Rioux, N / 2000 / The induction of cyclooxygenase-1 by a tobacco carcinogen in U937 human macrophages is correlated to the activation of NF-kappaB / Carcinogenesis 21:1745
Beg, A. A. / 1996 / An essential role for NF-κB in preventing TNF-alpha-induced cell death / Science 274:782
Wu, M. / 1996 / Inhibition of NF-kappaB/ReI induces apoptosis of murine B cells / EMBO J 15:4682
Wang, C. Y / 1996 / TNF and cancer therapy-induced apoptosis / Science 274:784
Rioux, N / 2000 / The induction of cyclooxygenase-1 by a tobacco carcinogen in U937 human macrophages is correlated to the activation of NF-kappaB / Carcinogenesis 21:1745
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