지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 29 - 37 (9page)
이용수
초록· 키워드
오류제보하기
Purpose: The aim of this study was to observe the bony change in the OVX rat longitudinally and to study the alendronate effect. Materials and Methods: Eighteen Sprague-Dewley rats, eight-week old each, were randomly assigned into three groups: one of those sham-operated (N=4), the other two were OVX: saline-treated (N=7) and alendronate-treated group (N=7). The saline-treated group was administered with saline solution (0.1mL/100g) daily, while the alendronate-treated group was given alendronate (1mg/kg, Sigma-Aldrich Corp. Korea) daily. Micro-CT scannings of the lumbar were consecutively done at baseline, at 3-week intervals during 9 weeks. Two and three dimensional bony analysis were done. Bone mineral density (BMD) was measured with Piximus (GE Lunar Co. USA). The average values of these three methods were compared with each group. Results: After 6 weeks the BMD of the OVX group showed lower tendency than that of sham group. After 6 weeks many 3D parameters of micro-CT showed higher values in the OVX-alendronate group compared with the OVXsaline group. Most 2D bony parameters were higher in the OVX-alendronate group compared with the OVX-saline group at 9 weeks. Conclusion: This study showed low BMD of the OVX group after 6 weeks and showed the effect of alendronate on the BMD and bony structures of ovariectomized rats. This study also showed usefulness of in vivo micro-CT in monitoring individual bone changes over time.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Bone Mineral Density Changes after Ovariectomy in Rats as an Osteopenic Model : Stepwise Description of Double Dorso-Lateral Approach
대한신경외과학회지
2010 .01
-
골형태분석법과 micro-CT를 이용한 골소주 특성에 대한 연구
대한구강악안면방사선학회지
2007 .01
-
Enhancement of peri-implant bone formation via parathyroid hormone administration in a rat model at risk for medication-related osteonecrosis of the jaw
Journal of Periodontal & Implant Science
2020 .01
-
한국인에 있어서 알렌드로네이트 제제의 제형간 유효성 및 순응도 비교
한국임상약학회지
2008 .01
-
Difference in Spinal Fusion Process in Osteopenic and Nonosteopenic Living Rat Models Using Serial Microcomputed Tomography
대한신경외과학회지
2017 .01
-
Effects of Dietary from Safflower Bud on the Osteoporosis in Ovariectomized Rats
대한의생명과학회지
2014 .09
-
에스트로겐이 난소가 제거된 흰쥐에 미치는 영향
한국가축위생학회지
2010 .01
-
The Efficacious Comparison of Three Major Anti-Osteoporotic Agents (Calcitonin, Raloxifene Hydrochloride and Alendronate Sodium) in Ovariectomized (OVX) Rats
한국실험동물학회 학술발표대회 논문집
2009 .08
-
척수손상환자에서 Alendronate 복용 후 골밀도의 증가
Annals of Rehabilitation Medicine
2005 .01
-
Study of acupuncture stimulation on experimental osteopenia
Oriental pharmacy and experimental medicine
2006 .01
-
The Change of Bone Metabolism in Ovariectomized Rats : Analyses of MicroCT Scan and Biochemical Markers of Bone Turnover
대한신경외과학회지
2012 .01
-
Single and Five-Week Oral Dose Toxicity Studies of Calcitriol and Alendronate Mixtures in Rats
Toxicological Research
2004 .09
-
자극(刺鍼)이 난소(卵巢)를 절제(切除)한 흰쥐의 골밀도(骨密度)에 미치는 영향(影響)
대한침구의학회지
1998 .01
-
L-carnitine이 난소가 제거된 흰쥐에 미치는 영향
한국가축위생학회지
2010 .01
-
폐경 후 골다공증 환자에서 지속적 호르몬 대체요법과 Alendronate의 병합치료
Annals of Rehabilitation Medicine
2002 .01
-
Effect of Intermittent Parathyroid Hormone Administration on the Microstructure of Jaw Bone in the Ovariectomized Rats
Journal of Korean Dental Science
2015 .12
-
Biodegradable Screws Containing Bone Morphogenetic Protein-2 in an Osteoporotic Rat Model
대한신경외과학회지
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0