Association Between High Neutrophil to Lymphocyte Ratio and Delayed Recovery From Bell's Palsy

김형식; 정준양; 동성화; 김상훈; 정수영; 여승근

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자료유형: 학술저널

저자정보: 김형식 정준양 동성화 김상훈 정수영 여승근

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제12권 제3호

발행연도: 2019.1

수록면: 261 - 266 (6page)

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Objectives. Factors predictive of the severity of and recovery from Bell’s palsy remain unclear. This study evaluated the association between neutrophil to lymphocyte ratio (NLR) and the severity of and recovery from Bell’s palsy. Methods. This retrospective study included 51 patients who were hospitalized with Bell’s palsy from 2015 to 2017. Degree of paralysis was assessed by House-Brackmann (H-B) grade. Patients with H-B grades 2–4 were classified as having mild to moderate palsy and patients with H-B grade 5 or 6 were classified as having severe palsy. Patients were evaluated for obesity, hypertension and diabetes mellitus, and blood tests were performed to determine NLR and platelet to lymphocyte ratio. Patients were treated with steroids and antiviral agents. H-B grade was assessed 1 week, 1 month, and 3 months after treatment. Results. NLR was significantly higher in patients with severe than with mild to moderate palsy (P=0.048). Recovery time was significantly longer in patients with high NLR than low NLR (P=0.045). Conclusion. Higher NLR in patients with Bell’s palsy was associated with longer recovery time. NLR may be prognostic of recovery time in patients with Bell’s palsy.

참고문헌 (28)

참고문헌 신청

De Diego JI / 1999 / Seasonal patterns of idiopathic facial paralysis : a 16-year study / Otolaryngol Head Neck Surg 120(2):269~271

Adour KK / 1975 / Herpes simplex virus in idiopathic facial paralysis(Bell palsy) / JAMA 233(6):527~530

Murakami S / 1996 / Bell palsy and herpes simplex virus: identification of viral DNA in endoneurial fluid and muscle / Ann Intern Med 124(1 Pt 1):27~30

Atan D / 2015 / New predictive parameters of bell’s palsy : neutrophil to lymphocyte ratio and platelet to lymphocyte ratio / Balkan Med J 32(2):167~170

Sahin C / 2017 / Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, mean platelet volume and red cell distribution width measures in bells palsy / Open Access Maced J Med Sci 5(1):14~18

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