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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 306 - 312 (7page)
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초록· 키워드
오류제보하기
Korean army dogs are raised for special purposes and have contributed much to society. However, several diseases occur in dogs. Canine hip dysplasia (CHD) is a musculoskeletal disorder that occurs frequently in Korean army dogs and interferes with their activities. If we could control CHD, this would have a positive effect on their performance. This study performed a genome-wide association study (GWAS) in 69 Korean army dogs to find significant loci for CHD using 170K single nucleotide polymorphisms (SNPs). CHD was classified according to the Norberg angle criterion. The control group comprised 62 dogs classified as relatively normal, and 7 dogs with severe CHD formed the case group. From the GWAS analysis, we concluded that SNPs present on chromosome 4 might have a significant impact on the overall expression of canine hip dysplasia.
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Zhou Z / 2010 / Differential genetic regulation of canine hip dysplasia and osteoarthritis / PLOS ONE 5:e13219
Schnelle G / 1935 / Some new diseases in the dog / Am Kennel Gaz 52:25~26
Spady TC / 2008 / Canine behavioral genetics : pointing out the phenotypes and herding up the genes / Am J Hum Genet 82:10~18
Bartolom N / 2015 / A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches / PLOS ONE 10:e0122558
Lavrijsen ICM / 2014 / Genome Wide Analysis Indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in labrador retrievers / PLOS ONE 9:e87735
Schnelle G / 1935 / Some new diseases in the dog / Am Kennel Gaz 52:25~26
Spady TC / 2008 / Canine behavioral genetics : pointing out the phenotypes and herding up the genes / Am J Hum Genet 82:10~18
Bartolom N / 2015 / A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches / PLOS ONE 10:e0122558
Lavrijsen ICM / 2014 / Genome Wide Analysis Indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in labrador retrievers / PLOS ONE 9:e87735
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