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논문 기본 정보

자료유형
학술저널
저자정보
Doo Ho Lee (Chungnam National University) Soo Hyun Lee (Chungnam National University) Ji Min Kang (Chungnam National University) Ho Young Ju (Department of Defense Military Observer Corps) Cheol Koo Lee (Korea University) Bong Hwan Choi (RDA) Seung Hwan Lee (Chungnam National University)
저널정보
충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.44 No.4
발행연도
2017.12
수록면
549 - 557 (9page)

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As exchanges between countries become more active, new threats such as drugs, illegal imports of food and medicines, and terrorism are present all over the world. From this, increased border security that protects people’s safety is becoming a new issue. The activities of special purpose dogs that detect these threats in advance are becoming very important. One of the obstacles in securing superior individuals is musculoskeletal disorders which interfere with the work of special purpose dogs. In order to search for genes associated with these genetic disorders, we conducted genomic analysis using linkage disequilibrium information and investigated genetic characteristics to know heterozygosity and inbreeding status in the population. In this study, two breeds (Malinois, Shepherd) of army dogs and three breeds (Malinois, Shepherd, Retriever) from public databases were used for comparison. The 170K SNP marker panel was used for this study. In the principal component analysis, it was confirmed that clusters were formed for each breed. The number of effective populations differed for each cultivar, but this was due to the difference in numbers of individuals for each breed used for the analysis. The results of heterozygosity decay analysis showed that heterozygous alleles decreased with each generation. In the army dog group, if the population number is maintained properly, the frequency of allele genotype will not decrease significantly.

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Abstract
Introduction
Materials and Methods
Results and Discussion
References

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UCI(KEPA) : I410-ECN-0101-2018-520-001702172