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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1 - 10 (10page)
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Background: It is known that large dogs who are fed lamb and rice diets are at increased risk to develop taurine-deficiency-induced dilated cardiomyopathy. Since dogs obligatorily conjugate bile acids (BA) with taurine, we determined whether rice bran (RB) or other fibers (cellulose; CL, beet pulp; BP) would affect BA excretion and/or the taurine status of dogs.
Results: Eighteen medium/large mixed-breed dogs were given purified diets containing CL, BP, or RB for 12 weeks.
Taurine concentrations in plasma and whole blood were significantly decreased at week 12. The BP group, compared to the CL or RB groups, showed significantly lower taurine concentrations in plasma (6.5 ± 0.5 vs 20.4 ± 3.9 and 13.1 ± 2.0 μmol/L, respectively, P < 0.01, mean ± SEM) and in whole blood (79 ± 10 vs 143 ± 14 and 127 ± 14 μmol/L, respectively, P < 0.01), lower apparent protein digestibility (81.9 ± 0.6 vs 88.8 ± 0.6 and 88.1 ± 1.2 %, respectively, P < 0.01), and higher BA excretions (5.6 ± 0.1 vs 3.4 ± 0.5 and 3.4 ± 0.4 μmol/g feces, respectively, P < 0.05) at week 12.
Conclusions: These results do not support the hypothesis that RB is likely to be a primary cause of lamb meal and rice diets, increasing the risk of taurine deficiency in large dogs. However these indicate that BP may contribute to a decrease taurine status in dogs by increasing excretion of fecal BA and decreasing protein digestibility, thus decreasing the bioavailability of sulfur amino acids, the precursors of taurine.
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참고문헌 (38)
참고문헌 신청
Hayes KC / 1998 / Taurine nutrition / Nutr Res Rev 1:99~113
Torres CL / 2003 / The effects of dietary ingredients, bacterial degradation in the gut and amount of food consumed on taurine status of dogs of different body sizes (dissertation) / University of California Davis
Backus RC / 2003 / Taurine deficiency in Newfoundlands fed commercially available complete and balanced diets / J Am Vet Med Assoc 223:1130~1136
Backus RC / 2006 / Low plasma taurine concentrations in Newfoundland dogs is associated with low plasma methionine and cyst(e)ine concentrations and low taurine synthesis / J Nutr 136:2525~2533
Fascetti AJ / 2003 / Taurine deficiency in dogs with dilated cardiomyopathy: 12 cases (1997-2001) / J Am Vet Med Assoc 223:1137~1141
Torres CL / 2003 / The effects of dietary ingredients, bacterial degradation in the gut and amount of food consumed on taurine status of dogs of different body sizes (dissertation) / University of California Davis
Backus RC / 2003 / Taurine deficiency in Newfoundlands fed commercially available complete and balanced diets / J Am Vet Med Assoc 223:1130~1136
Backus RC / 2006 / Low plasma taurine concentrations in Newfoundland dogs is associated with low plasma methionine and cyst(e)ine concentrations and low taurine synthesis / J Nutr 136:2525~2533
Fascetti AJ / 2003 / Taurine deficiency in dogs with dilated cardiomyopathy: 12 cases (1997-2001) / J Am Vet Med Assoc 223:1137~1141
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