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자료유형
학술저널
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저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제33권 제5호
발행연도
2019.1
수록면
422 - 429 (8page)

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Purpose: We investigated changes in the thickness of the peripapillary retinal nerve fiber layer (RNFL) followingthe onset of an epiretinal membrane (ERM) in glaucoma patients. Methods: Among regularly monitored glaucoma patients, patients with a newly diagnosed ERM were consecutivelyenrolled. Before and after the onset of ERM, the RNFL thickness was measured using spectral domainoptical coherence tomography, and a visual field examination was performed using a Humphrey field analyzer. Changes in RNFL thickness parameters and global indices of the visual field analyzer were assessed. Results: In a total of 28 eyes from 28 patients, the average RNFL thickness increased by a mean of 4.0 ± 7.4μm (p = 0.009) after ERM onset. There was an increase in the superior, nasal, and temporal quadrant RNFLthicknesses, and the change in the temporal RNFL thickness was significant (14.4 ± 21.2 μm, p < 0.001). However,the inferior RNFL thickness decreased by -0.6 ± 7.5 μm (p = 0.116). In the visual field examination, themean deviation decreased significantly by -0.8 ± 1.7 dB (p = 0.038), from -14.6 to -15.4 dB. Conclusions: A significant increase in average RNFL thickness was detected following ERM onset in glaucomapatients, although there was deterioration of the mean deviation in the visual field. When ERM occurs inglaucoma patients, clinicians should be aware that RNFL thickness measurements obtained with a spectraldomain optical coherence tomography may underestimate the status of glaucomatous optic neuropathy.

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