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논문 기본 정보

자료유형
학술저널
저자정보
Nala Shin (Chungnam National University Hospital) 박지석 (충남대학교) 김경남 (충남대학교(의대)) 황영훈 (충남대학교병원)
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제36권 제6호
발행연도
2022.12
수록면
493 - 500 (8page)
DOI
10.3341/kjo.2022.0048

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초록· 키워드

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Purpose: To evaluate the dynamic range of retinal nerve fiber layer (RNFL) and optic nerve head (ONH) parameters measuredusing optical coherence tomography (OCT) in conditions ranging from nonglaucomatous status to advanced glaucoma by longitudinalobservation.Methods: A total of 15 eyes from 12 participants with glaucoma progression from a nonglaucomatous status to advancedglaucoma were included. The RNFL and ONH parameters were compared between the nonglaucomatous and advanced stageswithin the same eye. The absolute and relative changes in OCT parameters were analyzed.Results: The median highest intraocular pressure was 42.5 mmHg (interquartile range, 37.5to54.5 mmHg), and the finalmean deviation of the visual field test was –24.68 dB (interquartile range, –23.93 to –31.13 dB). The median relative changesin RNFL thickness were –40.6% in the overall area, and –51.9%, –21.4%, –51.1%, and –41.8% in the superior, nasal, inferior,and temporal quadrants, respectively (all p < 0.05). Relative changes in the rim area, disc area, average cup to disc ratio, verticalcup to disc ratio, and cup volume were –56.64%, 0.59%, 62.10%, 66.0%, and 337.90%, respectively (all p < 0.05, except fordisc area with a p-value of 0.753).Conclusions: The dynamic range of the RNFL thickness ranged from 40.6% to 51.9%, and the dynamic range of the ONH parametersranged from 56.64% to 337.90%. During the course of glaucoma progression, the cup volume showed the widestdynamic range. However, the disc area did not show significant changes.

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