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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 158 - 163 (6page)
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초록· 키워드
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Brucellosis is one of the most important zoonotic diseases that lead to a great amount of economic losses. Prevention and diagnosis are both necessary to eradicate this disease. The identification and evaluation of different antigens of Brucella spp. play a key role in the progress of diagnostic programs. In this study, we designed, produced, and evaluated a 24-kDa polypeptide containing antigenic epitopes of VirB2, 3, and 9 of Brucella abortus for use with the ELISA kit. The produced polypeptide is appropriate for diagnosing brucellosis in bovines by a laboratory diagnostic kit, with 100% sensitivity and 97.5% specificity.
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등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Samaha H / 2008 / Multicenter study of brucellosis in Egypt / Emerg. Infect. Dis 14:1916~1918
Poester FP / 2013 / Pathogenesis and pathobiology of brucellosis in livestock / Rev. Sci. Tech 32:105~115
Celli J / 2003 / Brucella evades macrophage killing via VirBdependent sustained interactions with the endoplasmic reticulum / J. Exp. Med 198:545~556
Chumakov MI / 1998 / Localization of the protein VirB1 involved in contact formation during conjugation among Agrobacterium cells / FEMS Microbiol. Lett 168:297~301
Bellaire BH / 2005 / Opsonized virulent Brucella abortus replicates within nonacidic, endoplasmic reticulum-negative, LAMP-1-positive phagosomes in human monocytes / Infect Immun 73:3702~3713
Poester FP / 2013 / Pathogenesis and pathobiology of brucellosis in livestock / Rev. Sci. Tech 32:105~115
Celli J / 2003 / Brucella evades macrophage killing via VirBdependent sustained interactions with the endoplasmic reticulum / J. Exp. Med 198:545~556
Chumakov MI / 1998 / Localization of the protein VirB1 involved in contact formation during conjugation among Agrobacterium cells / FEMS Microbiol. Lett 168:297~301
Bellaire BH / 2005 / Opsonized virulent Brucella abortus replicates within nonacidic, endoplasmic reticulum-negative, LAMP-1-positive phagosomes in human monocytes / Infect Immun 73:3702~3713
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