지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제24권 제3호
- 발행연도
- 2019.1
- 수록면
- 195 - 198 (4page)
이용수
초록· 키워드
오류제보하기
Primary hyperparathyroidism (PHPT) and familial hypocalciuric hypercalcemia (FHH) have significantly different treatment approaches, so physicians must be careful to differentiate these 2 diseases. Herein, we report a 14-year-old female who presented with symptomatic hypercalcemia (12 mg/dL; reference range, 9.2–10.7 mg/dL), elevated intact parathyroid hormone (iPTH) (236 pg/mL; reference range, 9–69 pg/mL), and vitamin D deficiency (6 ng/mL; reference range, ≥ 20 ng/mL). On numerous occasions, her 24-hour urine calcium was more than 4 mg/kg/day, consistent with PHPT, but her fractional excretion of calcium on 24-hour urine collection was consistently below 1%, in line with FHH. 99mTc-Sestamibi scan failed to detect any abnormalities. However, a 4-dimensional computed tomography scan of the neck revealed a right superior parathyroid adenoma which was excised with a focused parathyroidectomy. Although the patient’s calcium and iPTH levels normalized, her nonspecific symptoms persisted. This case illustrates both the challenges of differentiating PHPT from FHH and the limitations of a first-line imaging tool in identifying a parathyroid adenoma.
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Roizen J, Levine MA / 2012 / Primary hyperparathyroidism in children and adolescents / J Chin Med Assoc 75:425~434
Tosur M / 2018 / Incidental hypercalcemia caused by primary hyperparathyroidism with rapid progression to renal complications in a child / Clin Pediatr (Phila) 57:117~120
Shinall MC Jr / 2013 / Differentiating familial hypocalciuric hypercalcemia from primary hyperparathyroidism / Endocr Pract 19:697~702
Bilezikian JP / 2002 / Summary statement from a workshop on asymptomatic primary hyperparathyroidism:a perspective for the 21st century / J Clin Endocrinol Metab 87:5353~5361
Christensen SE / 2008 / Discriminative power of three indices of renal calcium excretion for the distinction between familial hypocalciuric hypercalcaemia and primary hyperparathyroidism: a follow-up study on methods / Clin Endocrinol (Oxf) 69:713~720
Tosur M / 2018 / Incidental hypercalcemia caused by primary hyperparathyroidism with rapid progression to renal complications in a child / Clin Pediatr (Phila) 57:117~120
Shinall MC Jr / 2013 / Differentiating familial hypocalciuric hypercalcemia from primary hyperparathyroidism / Endocr Pract 19:697~702
Bilezikian JP / 2002 / Summary statement from a workshop on asymptomatic primary hyperparathyroidism:a perspective for the 21st century / J Clin Endocrinol Metab 87:5353~5361
Christensen SE / 2008 / Discriminative power of three indices of renal calcium excretion for the distinction between familial hypocalciuric hypercalcaemia and primary hyperparathyroidism: a follow-up study on methods / Clin Endocrinol (Oxf) 69:713~720
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