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논문 기본 정보

자료유형
학술저널
저자정보
Hyeokjoo Jang (Yonsei University Wonju College of Medicine) Seunghyun Lee (Yonsei University Wonju College of Medicine) Dahee Kim (Yonsei University Wonju College of Medicine) Namki Hong (Yonsei University Wonju College of Medicine)
저널정보
대한골대사학회 대한골대사학회지 대한골대사학회지 제29권 제3호
발행연도
2022.8
수록면
197 - 203 (7page)

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Ectopic parathyroid adenomas of the retropharyngeal space are relatively rare. Herein, we report a case of primary hyperparathyroidism (PHPT) secondary to a retropharyn- geal parathyroid adenoma. A 22-year-old woman presented with elevated serum calci- um and parathyroid hormone (PTH) levels, revealed during a medical check-up. The pa- tient had a history of ureteral stones and a confirmed low bone mass. Neck 99mTechne- tium-sestamibi singlephoton emission computed tomography (CT) and ultrasonogra- phy did not reveal any suspicious lesions. There was no evidence of hereditary PHPT based on the results of targeted gene sequencing. Surgical exploration was unsuccess- ful, and the PHPT persisted after the first surgery. Approximately a year after the failed operation, 18F-fluorocholine (FCH) positron emission tomography/CT (PET-CT) became available, and when performed, it revealed increased uptake in the retropharyngeal space of the right side of the neck. The results of parathyroid venous sampling were con- cordant with a >2-fold elevation of PTH level in the veins on the right side of the neck compared to the peripheral veins. The 1.8 cm-diameter mass was successfully removed resulting in an 87% reduction in intraoperative PTH level (198.0-26.5 pg/mL). Subse- quently, normalizations of calcium and PTH levels were achieved. In summary, ectopic parathyroid adenomas, including retropharyngeal lesions, should also be suspected when investigating an elusive case of PHPT. 18F-FCH PET-CT can be a useful complemen- tary modality for detecting culprit lesions.

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