Surgical Outcomes of Subtotal Parathyroidectomy for Renal Hyperparathyroidism

김민송; 김근호; 이창화; 박준성; 이지영; 태경

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자료유형: 학술저널

저자정보: 김민송 김근호 이창화 박준성 이지영 태경

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제13권 제2호

발행연도: 2020.1

수록면: 173 - 178 (6page)

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Objectives. The aim of this study was to evaluate the effectiveness of subtotal parathyroidectomy for patients with renal hyperparathyroidism. Methods. We studied 25 patients with renal hyperparathyroidism who underwent subtotal parathyroidectomy from October 2002 to October 2017. We analyzed serum intact parathyroid hormone (iPTH), calcium, and inorganic phosphorus levels before and at multiple time points following surgery, and evaluated the surgical outcomes and complications. Results. Of the 25 patients, 13 (52%) were male and 12 (48%) were female, and the mean age was 53.4±9.3 years. The mean duration of dialysis before parathyroidectomy was 156.8±79.5 months. Mean preoperative serum iPTH and calcium levels were 1,199.0±571.3 pg/mL and 10.5±1.0 mg/dL, respectively. At 6 months postoperatively, the mean iPTH and calcium levels decreased to 49.2±47.6 pg/mL (P<0.01) and 8.0±1.0 mg/dL (P<0.01), respectively. Recurrent hyperparathyroidism occurred in two patients: one subsequently underwent kidney transplantation and the other continued hemodialysis and maintained normal calcium levels. One patient developed postoperative permanent hypoparathyroidism. Conclusion. Subtotal parathyroidectomy is a safe and effective surgical treatment for renal hyperparathyroidism.

참고문헌 (23)

참고문헌 신청

Madorin C / 2012 / The surgical management of renal hyperparathyroidism / Eur Arch Otorhinolaryngol 269(6):1565~1576

Cunningham J / 2011 / Secondary hyperparathyroidism : pathogenesis, disease progression, and therapeutic options / Clin J Am Soc Nephrol 6(4):913~921

Saliba W / 2009 / Secondary hyperparathyroidism : pathophysiology and treatment / J Am Board Fam Med 22(5):574~581

Jimenez Vibora E / 2005 / Renal hyperparathyroidism’s control after subtotal parathyroidectomy / Nefrologia 25(4):416~421

Konturek A / 2016 / Subtotal parathyroidectomy for secondary renal hyperparathyroidism : a 20-year surgical outcome study / Langenbecks Arch Surg 401(7):965~974

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