지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 144 - 151 (8page)
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초록· 키워드
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Background/Aims: This study aimed to evaluate the diagnostic accuracy of dual-focus narrow-band imaging (dNBI) andLugol’schromoendoscopy (LCE) combined with probe-based confocal laser endomicroscopy (pCLE) to screen for esophageal squamouscell neoplasms (ESCNs) in patients with a history of head and neck cancer. Methods: From March to August 2016, dNBI was performed. Next, LCE was performed, followed by pCLE and biopsy. Histology hashistorically been the gold standard to diagnose ESCN. The sensitivity, specificity, positive predictive value (PPV), negative predictivevalue (NPV), and accuracy of dNBI and LCE adjunct with pCLE were determined. Results: Twenty-four patients were included. Ten ESCNs were found in 8 patients (33%). Forty percent of high-graded intraepithelialneoplasias and all low-grade intraepithelial neoplasias were overlooked by dNBI. The sensitivity, specificity, PPV, NPV, and accuracy ofdNBI vs. LCE combined with pCLE were 50% vs. 80%, 62% vs. 67%, 36% vs. 44%, 75% vs. 91%, and 83% vs. 70%, respectively. Conclusions: The use of dNBI to detect ESCN was suboptimal. LCE with pCLE following dNBI had additional value for detectingesophageal dysplasia not detected by dNBI. The use of pCLE to detect dNBI-missed lesions yielded a high NPV, while pCLE-guidedbiopsy could reduce the number of unnecessary biopsies.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Jemal A / 2011 / Global cancer statistics / CA Cancer J Clin 61:69~90
Wang GQ / 2004 / Long-term results of operation for 420 patients with early squamous cell esophageal carcinoma discovered by screening / Ann Thorac Surg 77:1740~1744
Rustgi AK / 2014 / Esophageal carcinoma / N Engl J Med 371:2499~2509
Katada C / 2007 / Clinical outcome after endoscopic mucosal resection for esophageal squamous cell carcinoma invading the muscularis mucosae--a multicenter retrospective cohort study / Endoscopy 39:779~783
Hirota WK / 2006 / ASGE guideline : the role of endoscopy in the surveillance of premalignant conditions of the upper GI tract / Gastrointest Endosc 63:570~580
Wang GQ / 2004 / Long-term results of operation for 420 patients with early squamous cell esophageal carcinoma discovered by screening / Ann Thorac Surg 77:1740~1744
Rustgi AK / 2014 / Esophageal carcinoma / N Engl J Med 371:2499~2509
Katada C / 2007 / Clinical outcome after endoscopic mucosal resection for esophageal squamous cell carcinoma invading the muscularis mucosae--a multicenter retrospective cohort study / Endoscopy 39:779~783
Hirota WK / 2006 / ASGE guideline : the role of endoscopy in the surveillance of premalignant conditions of the upper GI tract / Gastrointest Endosc 63:570~580
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