지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제26권 제3호
- 발행연도
- 2016.1
- 수록면
- 477 - 482 (6page)
이용수
초록· 키워드
오류제보하기
A uridine diphosphate-glucose:sterol glycosyltransferase-encoding gene was isolated and cloned from the established fosmid library of Micromonospora rhodorangea ATCC 27932 that usually produces the aminoglycoside antibiotic geneticin. The gene consists of 1,185 base pairs and encodes a 41.4 kDa protein, which was heterologously expressed in Escherichia coli BL21(DE3). In silico analyses of the deduced gene product suggested that it is a member of the family 1 glycosyltransferases. The recombinant protein MrSGT was able to catalyze the transfer of a glucosyl moiety onto the C-3 hydroxy function in sterols (β-sitosterol, campesterol, and cholesterol), resulting in the corresponding steryl glucosides (β-sitosterol-3- O-β-D-glucoside, campesterol-3-O-β-D-glucoside, and cholesterol-3-O-β-D-glucoside). This enzyme prefers phytosterols to cholesterol, and also shows substrate flexibility to some extent, in that it could recognize a number of acceptor substrates.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
안병찬 / 2009 / Formation of Flavone Di-O-Glucosides Using a Glycosyltransferase from Bacillus cereus / Journal of Microbiology and Biotechnology 19(4):387~390
Akhisa T / 1991 / Physiology and Biochemistry of Sterols / American Oil Chemists’ Society :172~228
Bowles D / 2005 / Glycosyltransferases: managers of small molecules / Curr. Opin. Plant Biol 8:254~263
Chaturvedi P / 2011 / Sterol glycosyltransferases - the enzymes that modify sterols / Appl. Biochem. Biotechnol 165:47~68
Del Gobbo LC / 2015 / Are phytosterols responsible for the low-density lipoprotein-lowering effects of tree nuts?: a systematic review and meta-analysis / J. Am. Coll. Cardiol 65:2765~2767
Akhisa T / 1991 / Physiology and Biochemistry of Sterols / American Oil Chemists’ Society :172~228
Bowles D / 2005 / Glycosyltransferases: managers of small molecules / Curr. Opin. Plant Biol 8:254~263
Chaturvedi P / 2011 / Sterol glycosyltransferases - the enzymes that modify sterols / Appl. Biochem. Biotechnol 165:47~68
Del Gobbo LC / 2015 / Are phytosterols responsible for the low-density lipoprotein-lowering effects of tree nuts?: a systematic review and meta-analysis / J. Am. Coll. Cardiol 65:2765~2767
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Biosynthesis of Three Chalcone β-D-glucosides by Glycosyltransferase from Bacillus subtilis ATCC 6633
한국미생물·생명공학회지
2021 .01
-
Biosynthesis of Novel Glucosides Geldanamycin Analogs by Enzymatic Synthesis
Journal of Microbiology and Biotechnology
2016 .01
-
Glycosylation of Semi-Synthetic Isoflavene Phenoxodiol with a Recombinant Glycosyltransferase from Micromonospora echinospora ATCC 27932
Journal of Microbiology and Biotechnology
2022 .05
-
Bioconversion of Tetracycline Antibiotics to Novel Glucoside Derivatives by Single-Vessel Multienzymatic Glycosylation
Journal of Microbiology and Biotechnology
2018 .01
-
Biosynthesis of Apigenin Glucosides in Engineered Corynebacterium glutamicum
Journal of Microbiology and Biotechnology
2024 .05
-
Taxonomic Characterization and Antimicrobial Potential of Micromonospora Strains Isolated from River Side Soil
한국미생물학회 학술대회논문집
2020 .10
-
Genome Based Analysis of Antimicrobial Potential of a Micromonospora Strain Isolated from Riverside Soil
한국미생물학회 학술대회논문집
2021 .08
-
Validation and Application of LC-MS/MS Method for Quantification of Cyanogenic Glucosides in Domestic Commercial Food Samples
한국분석과학회 학술대회
2023 .05
-
Taxonomic Diversity and Antimicrobial Potential of Micromonospora spp. Isolated from Riverside Soil
한국미생물학회 학술대회논문집
2019 .04
-
Hanseniaspora thailandica BC9 β-Glucosidase for the Production of β-D-Hexyl Glucoside
Journal of Microbiology and Biotechnology
2018 .01
-
Functional Characterization of EKC/KEOPS Complex in the Fungal Sterol Regulation
한국미생물학회 학술대회논문집
2017 .04
-
Functional Characterization of Transcription Factors, Hob1 and Sre1, Regulating Sterol-biosynthesis in Pathogenic Cryptococcus Species Complex
한국미생물학회 학술대회논문집
2017 .04
-
Luteolin and luteolin-7-O-glucoside protect against acute liver injury through regulation of inflammatory mediators and antioxidative enzymes in GalN/LPS-induced hepatitic ICR mice
Nutrition Research and Practice
2019 .12
-
Luteolin and luteolin-7-O-glucoside protect against acute liver injury through regulation of inflammatory mediators and antioxidative enzymes in GalN/LPS-induced hepatitic ICR mice
Nutrition Research and Practice
2019 .12
-
Altering UDP-Glucose Donor Substrate Specificity of Bacillus licheniformis Glycosyltransferase towards TDP-Glucose
Journal of Microbiology and Biotechnology
2019 .01
-
Development and Validation of HPLC UV Based Quantitative Analytical Method for Apigenin-7-O-glucoside in Matricaria chamomilla Extract
한국분석과학회 학술대회
2023 .05
-
Description and Antimicrobial Potential of Micromonospora humidus sp. nov., Isolated from Riverside Soil
한국미생물학회 학술대회논문집
2020 .10
-
Spatial distribution and origin of organic matters in an Arctic fjord system based on lipid biomarkers (n-alkanes and sterols)
극지연구소 초록집
2023 .07
-
Identification and Characterization of SrbB, a New Sterol Regulatory Element Binding Protein Involved in Regulation of the Hypoxia Response and Virulence in Aspergillus fumigatus
한국미생물학회 학술대회논문집
2015 .04
-
Anti-inflammatory and anti-cancer activities of sterol rich fraction of cultured marine microalga Nannochloropsis oculata
Algae
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0