메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Poly-γ-glutamic acid (γ-PGA) is a natural edible polypeptide in which glutamate is polymerized via γ-amide linkages. First, we assessed the eye irritancy potential of γ-PGA in rabbits. Additionally, we studied the effects of γ-PGA on corneal wound healing, due to the anti-inflammatory properties and water retaining abilities of γ-PGA. In this study, the effects of γ-PGA on corneal wound healing after an alkali burn were evaluated. Thirty eyes wounded by alkali burning in 30 white rabbits were divided into three groups: group A was treated with 0.1% 5,000 kDa γ-PGA for 2 days; group B was treated with 0.1% hyaluronic acid; and group C was not treated, as a control. The area of corneal epithelial defect was examined at 12, 24, 30, 36,42, and 48 h after corneal alkali wounding to determine initial wound healing. We found that γ-PGA promoted corneal wound healing, compared with controls, and showed similar effects to hyaluronic acid. These results indicate that γ-PGA stimulates corneal wound healing by an anti-inflammatory effect and enhancing cell migration and cell proliferation. γ-PGA is a promising biomaterial that may be a substitute for hyaluronic acid in corneal wound healing treatment.

목차

등록된 정보가 없습니다.

참고문헌 (25)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0