지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 757 - 763 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: In the present study, we tested whether the presence of metabolic syndrome (MetS) would worsen the
features of inflammation, plasma omega 3 fatty acid levels and antioxidant potential in treated hypertensive
patients. Materials and Methods: Two groups were classified by the components of MetS: a reference group of
treated hypertensive subjects: hypertension (HTN) group (n = 39) and with more than two additional MetS
components: HTN with Mets group (n = 40). We further compared the parameters between HTN group and HTN
with MetS group. Results: The results showed that age (p < 0.001) and body mass index (BMI) (p < 0.001) were
significantly different between HTN group and HTN with MetS group. Age- and BMI-adjusted total radical
trapping antioxidant potential (TRAP) (p < 0.01) was significantly lower, whereas age- and BMI-adjusted CD (p <
0.05) and interleukin (IL) 6 (p < 0.05) were significantly higher in HTN with MetS group than in HTN group.
Moreover, HTN with MetS group had significantly lower levels of age- and BMI-adjusted plasma phospholipid
eicosapentaenoic acid (EPA) than HTN group (p < 0.05). On the other hand, the levels of age- and BMI-adjusted
intracellular cell adhesion molecule-1 (ICAM-1), adiponectin and high molecular weight (HMW)-adiponectin were
not significantly different between the groups. Conclusion: In conclusion, our results showed increased
inflammatory marker, reduced antioxidant potential and EPA levels in treated hypertensive patients in the presence
of MetS, suggesting the importance of changes of therapeutic lifestyle to modify the features of MetS.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
/ 2000 / Steering Committee of the WHO Western Pacific Region, IASO & IOTF. The Asia-Pacific perspective: redefining obesity and its treatment. Australia
Ahotupa M / 1998 / Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation / Clin Biochem 31 : 257 ~ 261
Aizawa Y / 2007 / Clustering trend of components of metabolic syndrome / Int J Cardiol 121 : 117 ~ 118
Cuspidi C / 2004 / Metabolic syndrome and target organ damage in untreated essential hypertensives / J Hypertens 22 : 1991 ~ 1998
Expert Panel on Detection Evaluation, and Treatment of High Blood Cholesterol in Adults / 2001 / Executive Summary of The Third Report of The National Cholesterol Education
Ahotupa M / 1998 / Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation / Clin Biochem 31 : 257 ~ 261
Aizawa Y / 2007 / Clustering trend of components of metabolic syndrome / Int J Cardiol 121 : 117 ~ 118
Cuspidi C / 2004 / Metabolic syndrome and target organ damage in untreated essential hypertensives / J Hypertens 22 : 1991 ~ 1998
Expert Panel on Detection Evaluation, and Treatment of High Blood Cholesterol in Adults / 2001 / Executive Summary of The Third Report of The National Cholesterol Education
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