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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 466 - 476 (11page)
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초록· 키워드
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Background/Aims: This study aimed to evaluate the efficacy and safety of emergency variceal ligation for the prevention of rebleeding in cirrhotic patients who are found on initial endoscopy to have blood clots in the stomach but no actively bleeding esophageal and gastric varices or stigmata.
Methods: This study included 28 cirrhotic patients who underwent emergency prophylactic EVL and 41 who underwent an elective intervention between January 2009 and June 2014. Clinical outcomes were analyzed, including the rebleeding, 6-week mortality, and rebleeding-free survival rates.
Results: The rebleeding rate was higher in the emergency than in the elective group (28.6% vs. 7.3%, P=0.041). Multivariate analysis showed that emergency prophylactic EVL (odds ratio [OR] = 7.4, 95% confidence interval [CI]=1.634.8, P=0.012) and Child-Pugh score C (OR=10.6, 95% CI=1.4-80.8, P=0.022) were associated with rebleeding. In the emergency group, the gastric varices were associated with rebleeding (OR=12.0, 95% CI=1.7-83.5, P=0.012).
Conclusions: Emergency EVL may be associated with variceal rebleeding when blood clots are present in the stomach without active esophageal and gastric variceal bleeding or stigmata. Elective intervention should be considered as a safer strategy for preventing variceal rebleeding in this situation. (Clin Mol Hepatol 2016;22:466-476)
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Garcia-Tsao G / 2010 / Management of varices and variceal hemorrhage in cirrhosis / N Engl J Med 362:823~832
Garcia-Tsao G / 2007 / Practice Guidelines Committee of AASLD; Practice Parameters Committee of the ACG. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis / Hepatology 46:922~938
D’Amico G / 1999 / Pharmacological treatment of portal hypertension: an evidence-based approach / Semin Liver Dis 19:475~505
Bosch J / 2003 / Prevention of variceal rebleeding / Lancet 361:952~954
de Franchis R / 1992 / Why do varices bleed? / Gastroenterol Clin North Am 21:85~101
Garcia-Tsao G / 2007 / Practice Guidelines Committee of AASLD; Practice Parameters Committee of the ACG. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis / Hepatology 46:922~938
D’Amico G / 1999 / Pharmacological treatment of portal hypertension: an evidence-based approach / Semin Liver Dis 19:475~505
Bosch J / 2003 / Prevention of variceal rebleeding / Lancet 361:952~954
de Franchis R / 1992 / Why do varices bleed? / Gastroenterol Clin North Am 21:85~101
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