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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 487 - 494 (8page)
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초록· 키워드
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Background/Aims: Practice guidelines recommend endoscopic band ligation (EBL) and endoscopic variceal obturation (EVO) for bleeding from esophageal varices and fundal varices, respectively. However, the optimal treatment for bleeding from cardiac varices along the lesser curvature of the stomach (GOV1) remains undefined. This retrospective study compared the efficacy between EBL and EVO for bleeding from GOV1.
Methods: Patients treated by EBL or EVO via cyanoacrylate injection for bleeding from GOV1 were enrolled. Patients diagnosed with hepatocellular carcinoma or treated with endoscopic injection sclerotherapy were excluded.
Results: The study included 91 patients treated for bleeding from GOV1. The mean age was 56.3±10.9 years (mean±SD), and 78 of them (85.7%) were men. Overall, 51 and 40 patients were treated with EBL and EVO, respectively. A trend for a higher hemostasis rate was noted in the EVO group (100%) than in the EBL group (82.6%, P=0.078). Varices rebled in 15 patients during follow-up. The rebleeding rate was significantly higher in the EBL group than in the EVO group (P=0.004). During follow-up, 13 patients died (11 in the EBL group and 2 in the EVO group); the survival rate was marginally significant between two groups (P=0.050). The rebleeding-free survival rate was significantly higher in the EVO group than in the EBL group (P=0.001).
Conclusions: Compared to EBL, EVO offered significantly lower rebleeding rates, significantly higher rebleeding-free survival rates, and a trend for higher hemostasis and survival rates. EVO appears to be the better therapeutic option for bleeding from GOV1. (Clin Mol Hepatol 2016;22:487-494)
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Garcia-Tsao G / 2007 / Practice Guidelines Committee of the AASLD; Practice Parameters Committee of the ACG. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis / Hepatology 46:922~938
North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices / 1988 / Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study / N Engl J Med 319:983~989
Graham DY / 1981 / The course of patients after variceal hemorrhage / Gastroenterology 80:800~809
D’Amico G / 2003 / Cooperative Study Group. Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators / Hepatology 38:599~612
Stokkeland K / 2006 / Improved prognosis for patients hospitalized with esophageal varices in Sweden 1969- 2002 / Hepatology 43:500~505
North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices / 1988 / Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study / N Engl J Med 319:983~989
Graham DY / 1981 / The course of patients after variceal hemorrhage / Gastroenterology 80:800~809
D’Amico G / 2003 / Cooperative Study Group. Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators / Hepatology 38:599~612
Stokkeland K / 2006 / Improved prognosis for patients hospitalized with esophageal varices in Sweden 1969- 2002 / Hepatology 43:500~505
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